Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents

Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents

Some adolescents seek novelty, but it is unknown whether the brain circuits underlying this behaviour can be used to predict later, problematic behaviour. Here, authors show that diminished ventral striatal and prefrontal activity in response to anticipated rewards at age 14 in these individuals pre...

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Autores principales: Christian Büchel, Jan Peters, Tobias Banaschewski, Arun L. W. Bokde, Uli Bromberg, Patricia J. Conrod, Herta Flor, Dimitri Papadopoulos, Hugh Garavan, Penny Gowland, Andreas Heinz, Henrik Walter, Bernd Ittermann, Karl Mann, Jean-Luc Martinot, Marie-Laure Paillère-Martinot, Frauke Nees, Tomas Paus, Zdenka Pausova, Luise Poustka, Marcella Rietschel, Trevor W. Robbins, Michael N. Smolka, Juergen Gallinat, Gunter Schumann, Brian Knutson, the IMAGEN consortium
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/19ac0c202e7a480ca935ca7267d2f82c
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spelling oai:doaj.org-article:19ac0c202e7a480ca935ca7267d2f82c2021-12-02T17:06:14ZBlunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents10.1038/ncomms141402041-1723https://doaj.org/article/19ac0c202e7a480ca935ca7267d2f82c2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14140https://doaj.org/toc/2041-1723Some adolescents seek novelty, but it is unknown whether the brain circuits underlying this behaviour can be used to predict later, problematic behaviour. Here, authors show that diminished ventral striatal and prefrontal activity in response to anticipated rewards at age 14 in these individuals predicts problematic drug use at age 16.Christian BüchelJan PetersTobias BanaschewskiArun L. W. BokdeUli BrombergPatricia J. ConrodHerta FlorDimitri PapadopoulosHugh GaravanPenny GowlandAndreas HeinzHenrik WalterBernd IttermannKarl MannJean-Luc MartinotMarie-Laure Paillère-MartinotFrauke NeesTomas PausZdenka PausovaLuise PoustkaMarcella RietschelTrevor W. RobbinsMichael N. SmolkaJuergen GallinatGunter SchumannBrian Knutsonthe IMAGEN consortiumNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Christian Büchel
Jan Peters
Tobias Banaschewski
Arun L. W. Bokde
Uli Bromberg
Patricia J. Conrod
Herta Flor
Dimitri Papadopoulos
Hugh Garavan
Penny Gowland
Andreas Heinz
Henrik Walter
Bernd Ittermann
Karl Mann
Jean-Luc Martinot
Marie-Laure Paillère-Martinot
Frauke Nees
Tomas Paus
Zdenka Pausova
Luise Poustka
Marcella Rietschel
Trevor W. Robbins
Michael N. Smolka
Juergen Gallinat
Gunter Schumann
Brian Knutson
the IMAGEN consortium
Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
description Some adolescents seek novelty, but it is unknown whether the brain circuits underlying this behaviour can be used to predict later, problematic behaviour. Here, authors show that diminished ventral striatal and prefrontal activity in response to anticipated rewards at age 14 in these individuals predicts problematic drug use at age 16.
format article
author Christian Büchel
Jan Peters
Tobias Banaschewski
Arun L. W. Bokde
Uli Bromberg
Patricia J. Conrod
Herta Flor
Dimitri Papadopoulos
Hugh Garavan
Penny Gowland
Andreas Heinz
Henrik Walter
Bernd Ittermann
Karl Mann
Jean-Luc Martinot
Marie-Laure Paillère-Martinot
Frauke Nees
Tomas Paus
Zdenka Pausova
Luise Poustka
Marcella Rietschel
Trevor W. Robbins
Michael N. Smolka
Juergen Gallinat
Gunter Schumann
Brian Knutson
the IMAGEN consortium
author_facet Christian Büchel
Jan Peters
Tobias Banaschewski
Arun L. W. Bokde
Uli Bromberg
Patricia J. Conrod
Herta Flor
Dimitri Papadopoulos
Hugh Garavan
Penny Gowland
Andreas Heinz
Henrik Walter
Bernd Ittermann
Karl Mann
Jean-Luc Martinot
Marie-Laure Paillère-Martinot
Frauke Nees
Tomas Paus
Zdenka Pausova
Luise Poustka
Marcella Rietschel
Trevor W. Robbins
Michael N. Smolka
Juergen Gallinat
Gunter Schumann
Brian Knutson
the IMAGEN consortium
author_sort Christian Büchel
title Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
title_short Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
title_full Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
title_fullStr Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
title_full_unstemmed Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
title_sort blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/19ac0c202e7a480ca935ca7267d2f82c
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