Functional compensation precedes recovery of tissue mass following acute liver injury

The liver possesses the ability to regenerate following sudden injury. Here, the authors use single-cell RNA-sequencing and in situ transcriptional analyses to identify a new phase of liver regeneration in mice aimed at maintaining essential functions throughout the regenerative process.

Guardado en:

Detalles Bibliográficos
Autores principales:	Chad M. Walesky, Kellie E. Kolb, Carolyn L. Winston, Jake Henderson, Benjamin Kruft, Ira Fleming, Sungjin Ko, Satdarshan P. Monga, Florian Mueller, Udayan Apte, Alex K. Shalek, Wolfram Goessling
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/19ae1c964a6645e69ee2804af9f1cfd1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:19ae1c964a6645e69ee2804af9f1cfd1
record_format	dspace
spelling	oai:doaj.org-article:19ae1c964a6645e69ee2804af9f1cfd12021-12-02T15:37:21ZFunctional compensation precedes recovery of tissue mass following acute liver injury10.1038/s41467-020-19558-32041-1723https://doaj.org/article/19ae1c964a6645e69ee2804af9f1cfd12020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19558-3https://doaj.org/toc/2041-1723The liver possesses the ability to regenerate following sudden injury. Here, the authors use single-cell RNA-sequencing and in situ transcriptional analyses to identify a new phase of liver regeneration in mice aimed at maintaining essential functions throughout the regenerative process.Chad M. WaleskyKellie E. KolbCarolyn L. WinstonJake HendersonBenjamin KruftIra FlemingSungjin KoSatdarshan P. MongaFlorian MuellerUdayan ApteAlex K. ShalekWolfram GoesslingNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chad M. Walesky Kellie E. Kolb Carolyn L. Winston Jake Henderson Benjamin Kruft Ira Fleming Sungjin Ko Satdarshan P. Monga Florian Mueller Udayan Apte Alex K. Shalek Wolfram Goessling Functional compensation precedes recovery of tissue mass following acute liver injury
description	The liver possesses the ability to regenerate following sudden injury. Here, the authors use single-cell RNA-sequencing and in situ transcriptional analyses to identify a new phase of liver regeneration in mice aimed at maintaining essential functions throughout the regenerative process.
format	article
author	Chad M. Walesky Kellie E. Kolb Carolyn L. Winston Jake Henderson Benjamin Kruft Ira Fleming Sungjin Ko Satdarshan P. Monga Florian Mueller Udayan Apte Alex K. Shalek Wolfram Goessling
author_facet	Chad M. Walesky Kellie E. Kolb Carolyn L. Winston Jake Henderson Benjamin Kruft Ira Fleming Sungjin Ko Satdarshan P. Monga Florian Mueller Udayan Apte Alex K. Shalek Wolfram Goessling
author_sort	Chad M. Walesky
title	Functional compensation precedes recovery of tissue mass following acute liver injury
title_short	Functional compensation precedes recovery of tissue mass following acute liver injury
title_full	Functional compensation precedes recovery of tissue mass following acute liver injury
title_fullStr	Functional compensation precedes recovery of tissue mass following acute liver injury
title_full_unstemmed	Functional compensation precedes recovery of tissue mass following acute liver injury
title_sort	functional compensation precedes recovery of tissue mass following acute liver injury
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/19ae1c964a6645e69ee2804af9f1cfd1
work_keys_str_mv	AT chadmwalesky functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT kellieekolb functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT carolynlwinston functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT jakehenderson functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT benjaminkruft functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT irafleming functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT sungjinko functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT satdarshanpmonga functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT florianmueller functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT udayanapte functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT alexkshalek functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury AT wolframgoessling functionalcompensationprecedesrecoveryoftissuemassfollowingacuteliverinjury
_version_	1718386156300664832

Functional compensation precedes recovery of tissue mass following acute liver injury

Ejemplares similares