Skeletal Dysplasia Mutations Effect on Human Filamins’ Structure and Mechanosensing
Abstract Cells’ ability to sense mechanical cues in their environment is crucial for fundamental cellular processes, leading defects in mechanosensing to be linked to many diseases. The actin cross-linking protein Filamin has an important role in the conversion of mechanical forces into biochemical...
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Autores principales: | Jonne Seppälä, Rafael C. Bernardi, Tatu J. K. Haataja, Maarit Hellman, Olli T. Pentikäinen, Klaus Schulten, Perttu Permi, Jari Ylänne, Ulla Pentikäinen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/19baf53cadc947c297dabc4e0149c6e8 |
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