A Review of High-Intensity Focused Ultrasound in Urology

This review provides an introduction to high-intensity focused ultrasound (HIFU) and reviews its historical and current use in urological surgery. Current and historical literature (1927–2020), including that describing trials and review articles in the medical and ultrasonic literature, has been re...

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Autores principales:	David Cranston, Tom Leslie, Gail ter Haar
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	high-intensity focused ultrasound kidney cancer prostate prostatic carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/19be5feb4c4149a4a7915c575d9a68af
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spelling	oai:doaj.org-article:19be5feb4c4149a4a7915c575d9a68af2021-11-25T17:02:46ZA Review of High-Intensity Focused Ultrasound in Urology10.3390/cancers132256962072-6694https://doaj.org/article/19be5feb4c4149a4a7915c575d9a68af2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/22/5696https://doaj.org/toc/2072-6694This review provides an introduction to high-intensity focused ultrasound (HIFU) and reviews its historical and current use in urological surgery. Current and historical literature (1927–2020), including that describing trials and review articles in the medical and ultrasonic literature, has been reviewed, using Pub Med and Cochrane search engines. HIFU is currently one of a number of treatments for prostate cancer, both as a primary treatment that can be repeated, and as a salvage treatment post-radiotherapy. HIFU is not yet sufficiently mature to be a standard treatment for renal cancer or other urological diseases, although there has been some success in early clinical trials. As the technology improves, this situation is likely to change. HIFU has been understood as a concept for a century, and has been applied in experimental use for half that time. It is now an accepted treatment with low morbidity in many diseases outside the scope of this review. In urological surgery, prostate HIFU is accepted as a localised treatment in selected cases, with potentially fewer side effects than other localised therapies. Currently the treatment for renal cancer is hindered by the perinephric fat and the position of the kidneys behind the ribs; however, as the technology improves with image fusion, faster treatments, and the ability with phased array transducers and motion compensation to overcome the problems caused by the ribs and breathing, successful treatment of kidney tumours will become more of a reality. In due course, there will be a new generation of machines for treating prostate cancer. These devices will further minimise the side effects of radical treatment of prostate cancer.David CranstonTom LeslieGail ter HaarMDPI AGarticlehigh-intensity focused ultrasoundkidney cancerprostateprostatic carcinomaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5696, p 5696 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	high-intensity focused ultrasound kidney cancer prostate prostatic carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	high-intensity focused ultrasound kidney cancer prostate prostatic carcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 David Cranston Tom Leslie Gail ter Haar A Review of High-Intensity Focused Ultrasound in Urology
description	This review provides an introduction to high-intensity focused ultrasound (HIFU) and reviews its historical and current use in urological surgery. Current and historical literature (1927–2020), including that describing trials and review articles in the medical and ultrasonic literature, has been reviewed, using Pub Med and Cochrane search engines. HIFU is currently one of a number of treatments for prostate cancer, both as a primary treatment that can be repeated, and as a salvage treatment post-radiotherapy. HIFU is not yet sufficiently mature to be a standard treatment for renal cancer or other urological diseases, although there has been some success in early clinical trials. As the technology improves, this situation is likely to change. HIFU has been understood as a concept for a century, and has been applied in experimental use for half that time. It is now an accepted treatment with low morbidity in many diseases outside the scope of this review. In urological surgery, prostate HIFU is accepted as a localised treatment in selected cases, with potentially fewer side effects than other localised therapies. Currently the treatment for renal cancer is hindered by the perinephric fat and the position of the kidneys behind the ribs; however, as the technology improves with image fusion, faster treatments, and the ability with phased array transducers and motion compensation to overcome the problems caused by the ribs and breathing, successful treatment of kidney tumours will become more of a reality. In due course, there will be a new generation of machines for treating prostate cancer. These devices will further minimise the side effects of radical treatment of prostate cancer.
format	article
author	David Cranston Tom Leslie Gail ter Haar
author_facet	David Cranston Tom Leslie Gail ter Haar
author_sort	David Cranston
title	A Review of High-Intensity Focused Ultrasound in Urology
title_short	A Review of High-Intensity Focused Ultrasound in Urology
title_full	A Review of High-Intensity Focused Ultrasound in Urology
title_fullStr	A Review of High-Intensity Focused Ultrasound in Urology
title_full_unstemmed	A Review of High-Intensity Focused Ultrasound in Urology
title_sort	review of high-intensity focused ultrasound in urology
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/19be5feb4c4149a4a7915c575d9a68af
work_keys_str_mv	AT davidcranston areviewofhighintensityfocusedultrasoundinurology AT tomleslie areviewofhighintensityfocusedultrasoundinurology AT gailterhaar areviewofhighintensityfocusedultrasoundinurology AT davidcranston reviewofhighintensityfocusedultrasoundinurology AT tomleslie reviewofhighintensityfocusedultrasoundinurology AT gailterhaar reviewofhighintensityfocusedultrasoundinurology
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A Review of High-Intensity Focused Ultrasound in Urology

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