Alternative activation generates IL-10 producing type 2 innate lymphoid cells

Type 2 innate lymphoid cells (ILC2) are thought to be a uniform population of effector cells that produce IL-5 and IL-13. Here, the authors shown that, in mice, IL-33 can alternatively activate these cells to generate a molecularly distinct IL-10-producing subset designated ILC210.

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Autores principales:	Corey R. Seehus, Asha Kadavallore, Brian de la Torre, Alyson R. Yeckes, Yizhou Wang, Jie Tang, Jonathan Kaye
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/19c8c7f5c9a0482b93c72c88a8ce8cae
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spelling	oai:doaj.org-article:19c8c7f5c9a0482b93c72c88a8ce8cae2021-12-02T15:38:56ZAlternative activation generates IL-10 producing type 2 innate lymphoid cells10.1038/s41467-017-02023-z2041-1723https://doaj.org/article/19c8c7f5c9a0482b93c72c88a8ce8cae2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02023-zhttps://doaj.org/toc/2041-1723Type 2 innate lymphoid cells (ILC2) are thought to be a uniform population of effector cells that produce IL-5 and IL-13. Here, the authors shown that, in mice, IL-33 can alternatively activate these cells to generate a molecularly distinct IL-10-producing subset designated ILC210.Corey R. SeehusAsha KadavalloreBrian de la TorreAlyson R. YeckesYizhou WangJie TangJonathan KayeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Corey R. Seehus Asha Kadavallore Brian de la Torre Alyson R. Yeckes Yizhou Wang Jie Tang Jonathan Kaye Alternative activation generates IL-10 producing type 2 innate lymphoid cells
description	Type 2 innate lymphoid cells (ILC2) are thought to be a uniform population of effector cells that produce IL-5 and IL-13. Here, the authors shown that, in mice, IL-33 can alternatively activate these cells to generate a molecularly distinct IL-10-producing subset designated ILC210.
format	article
author	Corey R. Seehus Asha Kadavallore Brian de la Torre Alyson R. Yeckes Yizhou Wang Jie Tang Jonathan Kaye
author_facet	Corey R. Seehus Asha Kadavallore Brian de la Torre Alyson R. Yeckes Yizhou Wang Jie Tang Jonathan Kaye
author_sort	Corey R. Seehus
title	Alternative activation generates IL-10 producing type 2 innate lymphoid cells
title_short	Alternative activation generates IL-10 producing type 2 innate lymphoid cells
title_full	Alternative activation generates IL-10 producing type 2 innate lymphoid cells
title_fullStr	Alternative activation generates IL-10 producing type 2 innate lymphoid cells
title_full_unstemmed	Alternative activation generates IL-10 producing type 2 innate lymphoid cells
title_sort	alternative activation generates il-10 producing type 2 innate lymphoid cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/19c8c7f5c9a0482b93c72c88a8ce8cae
work_keys_str_mv	AT coreyrseehus alternativeactivationgeneratesil10producingtype2innatelymphoidcells AT ashakadavallore alternativeactivationgeneratesil10producingtype2innatelymphoidcells AT briandelatorre alternativeactivationgeneratesil10producingtype2innatelymphoidcells AT alysonryeckes alternativeactivationgeneratesil10producingtype2innatelymphoidcells AT yizhouwang alternativeactivationgeneratesil10producingtype2innatelymphoidcells AT jietang alternativeactivationgeneratesil10producingtype2innatelymphoidcells AT jonathankaye alternativeactivationgeneratesil10producingtype2innatelymphoidcells
_version_	1718386036628783104

Alternative activation generates IL-10 producing type 2 innate lymphoid cells

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