Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes

Psoriatic arthritis often develops in patients with psoriasis and can lead to joint deformity, stiffness, dysfunction, and disability. Psoriatic arthritis is a polygenic disease. and the issue of personalizing the prognosis of its development can only be resolved taking into account the variability...

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Autores principales:	Alexey A. Kubanov, Arfenya E. Karamova, Vadim V. Chikin, Dmitry A. Verbenko, Lyudmila F. Znamenskaya, Olga G. Artamonova
Formato:	article
Lenguaje:	RU
Publicado:	State Scientific Center of Dermatovenereology and Cosmetology 2021
Materias:	psoriatic arthritis genetic susceptibility genome-wide association study snp polygenic disease Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/19d39efd166f4066b47ef5f50dd45010
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spelling	oai:doaj.org-article:19d39efd166f4066b47ef5f50dd450102021-12-01T22:16:30ZGenetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes0042-46092313-629410.25208/vdv1260https://doaj.org/article/19d39efd166f4066b47ef5f50dd450102021-10-01T00:00:00Zhttps://vestnikdv.ru/jour/article/viewFile/1260/1231https://doaj.org/toc/0042-4609https://doaj.org/toc/2313-6294Psoriatic arthritis often develops in patients with psoriasis and can lead to joint deformity, stiffness, dysfunction, and disability. Psoriatic arthritis is a polygenic disease. and the issue of personalizing the prognosis of its development can only be resolved taking into account the variability of plenty genomic loci associated with the development of the disease. The personification of the prognosis of the disease can be solved taking into account the variability of the set of genomic loci with which its development is associated. The review examines genomic polymorphisms associated with the development of psoriatic arthritis not psoriasis, except of HLA polymorphisms. Genome regions containing polymorphisms, allelic variants of which are associated both with the development of psoriatic arthritis and reducing the likelihood of its occurrence, are described. It has been reported that the predisposition to the development of psoriatic arthritis in patients with psoriasis is determined by genes encoding proteins involved in inflammation and bone metabolism.Alexey A. KubanovArfenya E. KaramovaVadim V. ChikinDmitry A. VerbenkoLyudmila F. ZnamenskayaOlga G. ArtamonovaState Scientific Center of Dermatovenereology and Cosmetologyarticlepsoriatic arthritisgenetic susceptibilitygenome-wide association studysnppolygenic diseaseDermatologyRL1-803RUVestnik Dermatologii i Venerologii, Vol 97, Iss 4, Pp 33-47 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	psoriatic arthritis genetic susceptibility genome-wide association study snp polygenic disease Dermatology RL1-803
spellingShingle	psoriatic arthritis genetic susceptibility genome-wide association study snp polygenic disease Dermatology RL1-803 Alexey A. Kubanov Arfenya E. Karamova Vadim V. Chikin Dmitry A. Verbenko Lyudmila F. Znamenskaya Olga G. Artamonova Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes
description	Psoriatic arthritis often develops in patients with psoriasis and can lead to joint deformity, stiffness, dysfunction, and disability. Psoriatic arthritis is a polygenic disease. and the issue of personalizing the prognosis of its development can only be resolved taking into account the variability of plenty genomic loci associated with the development of the disease. The personification of the prognosis of the disease can be solved taking into account the variability of the set of genomic loci with which its development is associated. The review examines genomic polymorphisms associated with the development of psoriatic arthritis not psoriasis, except of HLA polymorphisms. Genome regions containing polymorphisms, allelic variants of which are associated both with the development of psoriatic arthritis and reducing the likelihood of its occurrence, are described. It has been reported that the predisposition to the development of psoriatic arthritis in patients with psoriasis is determined by genes encoding proteins involved in inflammation and bone metabolism.
format	article
author	Alexey A. Kubanov Arfenya E. Karamova Vadim V. Chikin Dmitry A. Verbenko Lyudmila F. Znamenskaya Olga G. Artamonova
author_facet	Alexey A. Kubanov Arfenya E. Karamova Vadim V. Chikin Dmitry A. Verbenko Lyudmila F. Znamenskaya Olga G. Artamonova
author_sort	Alexey A. Kubanov
title	Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes
title_short	Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes
title_full	Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes
title_fullStr	Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes
title_full_unstemmed	Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes
title_sort	genetic markers for psoriatic arthritis in patients with psoriasis. part i: non-hla genes
publisher	State Scientific Center of Dermatovenereology and Cosmetology
publishDate	2021
url	https://doaj.org/article/19d39efd166f4066b47ef5f50dd45010
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Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes

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