The role of insulin C-peptide in the coevolution analyses of the insulin signaling pathway: a hint for its functions.

As the linker between the A chain and B chain of proinsulin, C-peptide displays high variability in length and amino acid composition, and has been considered as an inert byproduct of insulin synthesis and processing for many years. Recent studies have suggested that C-peptide can act as a bioactive...

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Autores principales: Shuai Wang, Wei Wei, Yadong Zheng, Junling Hou, Yongxi Dou, Shaohua Zhang, Xuenong Luo, Xuepeng Cai
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/19d3cb7e42db44cbb6080d84b7d91a04
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