One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy

Abstract In the current study, a one‐pot method to prepare small lipid‐indocyanine green (ICG) nanoparticles (L‐ICG NPs) is proposed for the treatment of colorectal cancer. The L‐ICG NPs showed size distribution at around 20 nm with high stability and biocompatibility. In addition, they can respond...

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Autores principales:	Zhibin Bi, Lei Huang, Ming Han, Jun Ma, Peilong Wang
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	Chemical technology TP1-1185 Materials of engineering and construction. Mechanics of materials TA401-492
Acceso en línea:	https://doaj.org/article/19d41b80a9924a8292d41a0d8c7682f7
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spelling	oai:doaj.org-article:19d41b80a9924a8292d41a0d8c7682f72021-11-25T05:06:00ZOne‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy1750-044310.1049/mna2.12093https://doaj.org/article/19d41b80a9924a8292d41a0d8c7682f72021-11-01T00:00:00Zhttps://doi.org/10.1049/mna2.12093https://doaj.org/toc/1750-0443Abstract In the current study, a one‐pot method to prepare small lipid‐indocyanine green (ICG) nanoparticles (L‐ICG NPs) is proposed for the treatment of colorectal cancer. The L‐ICG NPs showed size distribution at around 20 nm with high stability and biocompatibility. In addition, they can respond to light irradiations to exert oxidative/thermal stress damage, which showed effective anticancer benefits in vitro and in vivo using HT‐29 cells as the model.Zhibin BiLei HuangMing HanJun MaPeilong WangWileyarticleChemical technologyTP1-1185Materials of engineering and construction. Mechanics of materialsTA401-492ENMicro & Nano Letters, Vol 16, Iss 13, Pp 636-642 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chemical technology TP1-1185 Materials of engineering and construction. Mechanics of materials TA401-492
spellingShingle	Chemical technology TP1-1185 Materials of engineering and construction. Mechanics of materials TA401-492 Zhibin Bi Lei Huang Ming Han Jun Ma Peilong Wang One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy
description	Abstract In the current study, a one‐pot method to prepare small lipid‐indocyanine green (ICG) nanoparticles (L‐ICG NPs) is proposed for the treatment of colorectal cancer. The L‐ICG NPs showed size distribution at around 20 nm with high stability and biocompatibility. In addition, they can respond to light irradiations to exert oxidative/thermal stress damage, which showed effective anticancer benefits in vitro and in vivo using HT‐29 cells as the model.
format	article
author	Zhibin Bi Lei Huang Ming Han Jun Ma Peilong Wang
author_facet	Zhibin Bi Lei Huang Ming Han Jun Ma Peilong Wang
author_sort	Zhibin Bi
title	One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy
title_short	One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy
title_full	One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy
title_fullStr	One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy
title_full_unstemmed	One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy
title_sort	one‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/19d41b80a9924a8292d41a0d8c7682f7
work_keys_str_mv	AT zhibinbi onepotpreparationofsmalllipidindocyaninegreennanoparticlestoinducedintracellularoxidativethermalstressdamageforeffectivecolorectalcancertherapy AT leihuang onepotpreparationofsmalllipidindocyaninegreennanoparticlestoinducedintracellularoxidativethermalstressdamageforeffectivecolorectalcancertherapy AT minghan onepotpreparationofsmalllipidindocyaninegreennanoparticlestoinducedintracellularoxidativethermalstressdamageforeffectivecolorectalcancertherapy AT junma onepotpreparationofsmalllipidindocyaninegreennanoparticlestoinducedintracellularoxidativethermalstressdamageforeffectivecolorectalcancertherapy AT peilongwang onepotpreparationofsmalllipidindocyaninegreennanoparticlestoinducedintracellularoxidativethermalstressdamageforeffectivecolorectalcancertherapy
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One‐pot preparation of small lipid‐indocyanine green nanoparticles to induced intracellular oxidative/thermal stress damage for effective colorectal cancer therapy

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