A Single Phosphorodiamidate Morpholino Oligomer Targeting VP24 Protects Rhesus Monkeys against Lethal Ebola Virus Infection

A Single Phosphorodiamidate Morpholino Oligomer Targeting VP24 Protects Rhesus Monkeys against Lethal Ebola Virus Infection

ABSTRACT Ebola viruses (EBOV) cause severe disease in humans and nonhuman primates with high mortality rates and continue to emerge in new geographic locations, including several countries in West Africa, the site of a large ongoing outbreak. Phosphorodiamidate morpholino oligomers (PMOs) are synthe...

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Bibliographic Details
Main Authors: Travis K. Warren, Chris A. Whitehouse, Jay Wells, Lisa Welch, Alison E. Heald, Jay S. Charleston, Pete Sazani, St. Patrick Reid, Patrick L. Iversen, Sina Bavari
Format: article
Language:EN
Published: American Society for Microbiology 2015
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/19d856969d434bf7a60886a465bb16a6
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