Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease

Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease

Summary: Non-alcoholic fatty liver disease (NAFLD) is a complex disease linked to several chronic diseases. We aimed at identifying genetic variants associated with NAFLD and evaluating their functional consequences. We performed a genome-wide meta-analysis of 4 cohorts of electronic health record-d...

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Autores principales: Nooshin Ghodsian, Erik Abner, Connor A. Emdin, Émilie Gobeil, Nele Taba, Mary E. Haas, Nicolas Perrot, Hasanga D. Manikpurage, Éloi Gagnon, Jérôme Bourgault, Alexis St-Amand, Christian Couture, Patricia L. Mitchell, Yohan Bossé, Patrick Mathieu, Marie-Claude Vohl, André Tchernof, Sébastien Thériault, Amit V. Khera, Tõnu Esko, Benoit J. Arsenault
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
genetics
non-alcoholic fatty liver disease
genome-wide association study
electronic health records
adipose tissue
lipoprotein lipase
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/19e306941a06424da1e769a90f8e839d
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https://doaj.org/article/19e306941a06424da1e769a90f8e839d

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