Life stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity

Abstract Inbreeding depression (ID) is a fundamental selective pressure that shapes mating systems and population genetic structures in plants. Although it has been shown that ID varies over the life stages of shorter-lived plants, less is known about how the fitness effects of inbreeding vary acros...

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Autores principales: Jon Ahlinder, Barbara E. Giles, M. Rosario García-Gil
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/19e68fc797a9403ba297602249db0802
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spelling oai:doaj.org-article:19e68fc797a9403ba297602249db08022021-12-02T13:39:55ZLife stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity10.1038/s41598-021-88128-42045-2322https://doaj.org/article/19e68fc797a9403ba297602249db08022021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88128-4https://doaj.org/toc/2045-2322Abstract Inbreeding depression (ID) is a fundamental selective pressure that shapes mating systems and population genetic structures in plants. Although it has been shown that ID varies over the life stages of shorter-lived plants, less is known about how the fitness effects of inbreeding vary across life stages in long-lived species. We conducted a literature survey in the Pinaceae, a tree family known to harbour some of the highest mutational loads ever reported. Using a meta-regression model, we investigated distributions of inbreeding depression over life stages, adjusting for effects of inbreeding levels and the genetic differentiation of populations within species. The final dataset contained 147 estimates of ID across life stages from 41 studies. 44 Fst estimates were collected from 40 peer-reviewed studies for the 18 species to aid genetic differentiation modelling. Partitioning species into fragmented and well-connected groups using Fst resulted in the best way (i.e. trade-off between high goodness-of-fit of the model to the data and reduced model complexity) to incorporate genetic connectivity in the meta-regression analysis. Inclusion of a life stage term and its interaction with the inbreeding coefficient (F) dramatically increased model precision. We observed that the correlation between ID and F was significant at the earliest life stage. Although partitioning of species populations into fragmented and well-connected groups explained little of the between-study heterogeneity, the inclusion of an interaction between life stage and population differentiation revealed that populations with fragmented distributions suffered lower inbreeding depression at early embryonic stages than species with well-connected populations. There was no evidence for increased ID in late life stages in well-connected populations, although ID tended to increase across life stages in the fragmented group. These findings suggest that life stage data should be included in inbreeding depression studies and that inbreeding needs to be managed over life stages in commercial populations of long-lived plants.Jon AhlinderBarbara E. GilesM. Rosario García-GilNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Jon Ahlinder
Barbara E. Giles
M. Rosario García-Gil
Life stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity
description Abstract Inbreeding depression (ID) is a fundamental selective pressure that shapes mating systems and population genetic structures in plants. Although it has been shown that ID varies over the life stages of shorter-lived plants, less is known about how the fitness effects of inbreeding vary across life stages in long-lived species. We conducted a literature survey in the Pinaceae, a tree family known to harbour some of the highest mutational loads ever reported. Using a meta-regression model, we investigated distributions of inbreeding depression over life stages, adjusting for effects of inbreeding levels and the genetic differentiation of populations within species. The final dataset contained 147 estimates of ID across life stages from 41 studies. 44 Fst estimates were collected from 40 peer-reviewed studies for the 18 species to aid genetic differentiation modelling. Partitioning species into fragmented and well-connected groups using Fst resulted in the best way (i.e. trade-off between high goodness-of-fit of the model to the data and reduced model complexity) to incorporate genetic connectivity in the meta-regression analysis. Inclusion of a life stage term and its interaction with the inbreeding coefficient (F) dramatically increased model precision. We observed that the correlation between ID and F was significant at the earliest life stage. Although partitioning of species populations into fragmented and well-connected groups explained little of the between-study heterogeneity, the inclusion of an interaction between life stage and population differentiation revealed that populations with fragmented distributions suffered lower inbreeding depression at early embryonic stages than species with well-connected populations. There was no evidence for increased ID in late life stages in well-connected populations, although ID tended to increase across life stages in the fragmented group. These findings suggest that life stage data should be included in inbreeding depression studies and that inbreeding needs to be managed over life stages in commercial populations of long-lived plants.
format article
author Jon Ahlinder
Barbara E. Giles
M. Rosario García-Gil
author_facet Jon Ahlinder
Barbara E. Giles
M. Rosario García-Gil
author_sort Jon Ahlinder
title Life stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity
title_short Life stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity
title_full Life stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity
title_fullStr Life stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity
title_full_unstemmed Life stage-specific inbreeding depression in long-lived Pinaceae species depends on population connectivity
title_sort life stage-specific inbreeding depression in long-lived pinaceae species depends on population connectivity
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/19e68fc797a9403ba297602249db0802
work_keys_str_mv AT jonahlinder lifestagespecificinbreedingdepressioninlonglivedpinaceaespeciesdependsonpopulationconnectivity
AT barbaraegiles lifestagespecificinbreedingdepressioninlonglivedpinaceaespeciesdependsonpopulationconnectivity
AT mrosariogarciagil lifestagespecificinbreedingdepressioninlonglivedpinaceaespeciesdependsonpopulationconnectivity
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