Kilogram synthesis of (R)-(-)-denopamine by Ir/f-amphox catalyzed asymmetric hydrogenation
A practical and efficient two-step synthetic process for the preparation of (R)-(-)-denopamine has been developed. The key step asymmetric hydrogenation was conducted at mild temperature (60 °C) under a hydrogen pressure of 50 atm by using Ir/f-amphox as catalyst at low catalyst loading (S/C = 2...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
KeAi Communications Co. Ltd.
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/19ed00e7bde540b28648ba550eba3ae8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|