Polygenic risk for obsessive-compulsive disorder (OCD) predicts brain response during working memory task in OCD, unaffected relatives, and healthy controls

Polygenic risk for obsessive-compulsive disorder (OCD) predicts brain response during working memory task in OCD, unaffected relatives, and healthy controls

Abstract Alterations in frontal and parietal neural activations during working memory task performance have been suggested as a candidate endophenotype of obsessive-compulsive disorder (OCD) in studies involving first-degree relatives. However, the direct link between genetic risk for OCD and neuro-...

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Autores principales: Stephan Heinzel, Christian Kaufmann, Rosa Grützmann, Julia Klawohn, Anja Riesel, Katharina Bey, Stefanie Heilmann-Heimbach, Leonie Weinhold, Alfredo Ramirez, Michael Wagner, Norbert Kathmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/19edda6e47d94e4e8d34ab02204182a9
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