Methylation of PhoP by CheR Regulates <i>Salmonella</i> Virulence
Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response regulator of PhoP/PhoQ two-component system, could b...
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American Society for Microbiology
2021
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oai:doaj.org-article:19f014700315414cbc5144d4ac08ed962021-11-03T21:52:35Z Methylation of PhoP by CheR Regulates <i>Salmonella</i> Virulence 2150-751110.1128/mBio.02099-21https://doaj.org/article/19f014700315414cbc5144d4ac08ed962021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02099-21https://doaj.org/toc/2150-7511 Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response regulator of PhoP/PhoQ two-component system, could be methylated on several evolutionally conserved amino acid residues.Yang SuJianhui LiWenting ZhangJinjing NiRui HuangZuoqiang WangSen ChengYue WangZhixin TianQiuxiang ZhouDonghai LinWenjuan WuChristoph M. TangXiaoyun LiuJie LuYu-Feng YaoAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Yang Su Jianhui Li Wenting Zhang Jinjing Ni Rui Huang Zuoqiang Wang Sen Cheng Yue Wang Zhixin Tian Qiuxiang Zhou Donghai Lin Wenjuan Wu Christoph M. Tang Xiaoyun Liu Jie Lu Yu-Feng Yao Methylation of PhoP by CheR Regulates <i>Salmonella</i> Virulence |
| description |
Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response regulator of PhoP/PhoQ two-component system, could be methylated on several evolutionally conserved amino acid residues. |
| format |
article |
| author |
Yang Su Jianhui Li Wenting Zhang Jinjing Ni Rui Huang Zuoqiang Wang Sen Cheng Yue Wang Zhixin Tian Qiuxiang Zhou Donghai Lin Wenjuan Wu Christoph M. Tang Xiaoyun Liu Jie Lu Yu-Feng Yao |
| author_facet |
Yang Su Jianhui Li Wenting Zhang Jinjing Ni Rui Huang Zuoqiang Wang Sen Cheng Yue Wang Zhixin Tian Qiuxiang Zhou Donghai Lin Wenjuan Wu Christoph M. Tang Xiaoyun Liu Jie Lu Yu-Feng Yao |
| author_sort |
Yang Su |
| title |
Methylation of PhoP by CheR Regulates
<i>Salmonella</i>
Virulence
|
| title_short |
Methylation of PhoP by CheR Regulates
<i>Salmonella</i>
Virulence
|
| title_full |
Methylation of PhoP by CheR Regulates
<i>Salmonella</i>
Virulence
|
| title_fullStr |
Methylation of PhoP by CheR Regulates
<i>Salmonella</i>
Virulence
|
| title_full_unstemmed |
Methylation of PhoP by CheR Regulates
<i>Salmonella</i>
Virulence
|
| title_sort |
methylation of phop by cher regulates
<i>salmonella</i>
virulence |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/19f014700315414cbc5144d4ac08ed96 |
| work_keys_str_mv |
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| _version_ |
1718445381250973696 |