Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food

Heliodoro Alemán-Mateo,1 Liliana Macías,1 Julián Esparza-Romero,1 Humberto Astiazaran-García,1 Ana Luz Blancas21Coordinación de Nutrición, Centro de Investigación en Alimentación y Desarrollo, AC, Hermosillo, Son...

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Autores principales:	Alemán-Mateo H, Macías L, Esparza-Romero J, Astiazaran-García H, Blancas AL
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Nutritional intervention protein-rich food ricotta cheese sarcopenia and elderly. Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/19f1d2a9cc124725a29cf4bfa41e3664
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spelling	oai:doaj.org-article:19f1d2a9cc124725a29cf4bfa41e36642021-12-02T07:45:32ZPhysiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food1178-1998https://doaj.org/article/19f1d2a9cc124725a29cf4bfa41e36642012-07-01T00:00:00Zhttps://www.dovepress.com/physiological-effects-beyond-the-significant-gain-in-muscle-mass-in-sa-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Heliodoro Alemán-Mateo,1 Liliana Macías,1 Julián Esparza-Romero,1 Humberto Astiazaran-García,1 Ana Luz Blancas21Coordinación de Nutrición, Centro de Investigación en Alimentación y Desarrollo, AC, Hermosillo, Sonora, México; 2Dirección General de Servicios de Salud a la Persona, Hermosillo, Sonora, MéxicoBackground: Sarcopenia is strongly associated with an inadequate intake of dietary protein. Dietary protein supplementation boosts muscle-protein synthesis and increases muscle mass in the elderly. This study tested whether adding a protein-rich food, ricotta cheese, to the habitual diet increased total appendicular skeletal muscle mass and strength in elderly people.Methods: Participants (n = 40), were sarcopenic elderly men and women over 60 years of age. Two comparison groups were formed at random and followed for 3 months: the intervention group received 210 g/day of ricotta cheese plus the habitual diet, while the control group followed the habitual diet with no additional intervention. Total appendicular skeletal muscle (TASM) was assessed by dual-energy X-ray absorptiometry, while strength was measured using a handheld dynamometer at baseline and after the intervention period. The primary outcomes were the percentage of relative change in TASM and strength.Results: The percentage of relative change in TASM was not significant between the groups after the intervention period. Muscle strength improved in the intervention group, but showed only a tendency towards significance (P = 0.06). Secondary analysis showed that the men in the intervention group gained 270 g in TASM compared to those in the control group, and improved their fasting insulin levels (P = 0.05), muscle strength, lean body mass in the arms, and body weight variables.Conclusion: The results of this study indicate that a nutritional intervention using a high-quality protein food, specifically ricotta cheese, in order to increase the amount of protein intake might not be regarded as fully promising in elderly men and women with sarcopenia. However, the gender effects on muscle strength, lean tissue in the arms, homeostatic assessment of insulin resistance, and body weight detected in this study suggest that additional research is needed on elderly male subjects with sarcopenia.Keywords: nutritional intervention, protein-rich food, ricotta cheese, sarcopenia, elderlyAlemán-Mateo HMacías LEsparza-Romero JAstiazaran-García HBlancas ALDove Medical PressarticleNutritional interventionprotein-rich foodricotta cheesesarcopenia and elderly.GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 7, Pp 225-234 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nutritional intervention protein-rich food ricotta cheese sarcopenia and elderly. Geriatrics RC952-954.6
spellingShingle	Nutritional intervention protein-rich food ricotta cheese sarcopenia and elderly. Geriatrics RC952-954.6 Alemán-Mateo H Macías L Esparza-Romero J Astiazaran-García H Blancas AL Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food
description	Heliodoro Alemán-Mateo,1 Liliana Macías,1 Julián Esparza-Romero,1 Humberto Astiazaran-García,1 Ana Luz Blancas21Coordinación de Nutrición, Centro de Investigación en Alimentación y Desarrollo, AC, Hermosillo, Sonora, México; 2Dirección General de Servicios de Salud a la Persona, Hermosillo, Sonora, MéxicoBackground: Sarcopenia is strongly associated with an inadequate intake of dietary protein. Dietary protein supplementation boosts muscle-protein synthesis and increases muscle mass in the elderly. This study tested whether adding a protein-rich food, ricotta cheese, to the habitual diet increased total appendicular skeletal muscle mass and strength in elderly people.Methods: Participants (n = 40), were sarcopenic elderly men and women over 60 years of age. Two comparison groups were formed at random and followed for 3 months: the intervention group received 210 g/day of ricotta cheese plus the habitual diet, while the control group followed the habitual diet with no additional intervention. Total appendicular skeletal muscle (TASM) was assessed by dual-energy X-ray absorptiometry, while strength was measured using a handheld dynamometer at baseline and after the intervention period. The primary outcomes were the percentage of relative change in TASM and strength.Results: The percentage of relative change in TASM was not significant between the groups after the intervention period. Muscle strength improved in the intervention group, but showed only a tendency towards significance (P = 0.06). Secondary analysis showed that the men in the intervention group gained 270 g in TASM compared to those in the control group, and improved their fasting insulin levels (P = 0.05), muscle strength, lean body mass in the arms, and body weight variables.Conclusion: The results of this study indicate that a nutritional intervention using a high-quality protein food, specifically ricotta cheese, in order to increase the amount of protein intake might not be regarded as fully promising in elderly men and women with sarcopenia. However, the gender effects on muscle strength, lean tissue in the arms, homeostatic assessment of insulin resistance, and body weight detected in this study suggest that additional research is needed on elderly male subjects with sarcopenia.Keywords: nutritional intervention, protein-rich food, ricotta cheese, sarcopenia, elderly
format	article
author	Alemán-Mateo H Macías L Esparza-Romero J Astiazaran-García H Blancas AL
author_facet	Alemán-Mateo H Macías L Esparza-Romero J Astiazaran-García H Blancas AL
author_sort	Alemán-Mateo H
title	Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food
title_short	Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food
title_full	Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food
title_fullStr	Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food
title_full_unstemmed	Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food
title_sort	physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/19f1d2a9cc124725a29cf4bfa41e3664
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Physiological effects beyond the significant gain in muscle mass in sarcopenic elderly men: evidence from a randomized clinical trial using a protein-rich food

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