Probing the physical limits of reliable DNA data retrieval

The physical limits and reliability of PCR-based random access of DNA encoded data is unknown. Here the authors demonstrate reliable file recovery from as few as ten copies per sequence, providing a data density limit of 17 exabytes per gram.

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Autores principales:	Lee Organick, Yuan-Jyue Chen, Siena Dumas Ang, Randolph Lopez, Xiaomeng Liu, Karin Strauss, Luis Ceze
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/19f23bb6a4994c2e9220827cf7e5fcf6
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spelling	oai:doaj.org-article:19f23bb6a4994c2e9220827cf7e5fcf62021-12-02T14:40:38ZProbing the physical limits of reliable DNA data retrieval10.1038/s41467-020-14319-82041-1723https://doaj.org/article/19f23bb6a4994c2e9220827cf7e5fcf62020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14319-8https://doaj.org/toc/2041-1723The physical limits and reliability of PCR-based random access of DNA encoded data is unknown. Here the authors demonstrate reliable file recovery from as few as ten copies per sequence, providing a data density limit of 17 exabytes per gram.Lee OrganickYuan-Jyue ChenSiena Dumas AngRandolph LopezXiaomeng LiuKarin StraussLuis CezeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lee Organick Yuan-Jyue Chen Siena Dumas Ang Randolph Lopez Xiaomeng Liu Karin Strauss Luis Ceze Probing the physical limits of reliable DNA data retrieval
description	The physical limits and reliability of PCR-based random access of DNA encoded data is unknown. Here the authors demonstrate reliable file recovery from as few as ten copies per sequence, providing a data density limit of 17 exabytes per gram.
format	article
author	Lee Organick Yuan-Jyue Chen Siena Dumas Ang Randolph Lopez Xiaomeng Liu Karin Strauss Luis Ceze
author_facet	Lee Organick Yuan-Jyue Chen Siena Dumas Ang Randolph Lopez Xiaomeng Liu Karin Strauss Luis Ceze
author_sort	Lee Organick
title	Probing the physical limits of reliable DNA data retrieval
title_short	Probing the physical limits of reliable DNA data retrieval
title_full	Probing the physical limits of reliable DNA data retrieval
title_fullStr	Probing the physical limits of reliable DNA data retrieval
title_full_unstemmed	Probing the physical limits of reliable DNA data retrieval
title_sort	probing the physical limits of reliable dna data retrieval
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/19f23bb6a4994c2e9220827cf7e5fcf6
work_keys_str_mv	AT leeorganick probingthephysicallimitsofreliablednadataretrieval AT yuanjyuechen probingthephysicallimitsofreliablednadataretrieval AT sienadumasang probingthephysicallimitsofreliablednadataretrieval AT randolphlopez probingthephysicallimitsofreliablednadataretrieval AT xiaomengliu probingthephysicallimitsofreliablednadataretrieval AT karinstrauss probingthephysicallimitsofreliablednadataretrieval AT luisceze probingthephysicallimitsofreliablednadataretrieval
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Probing the physical limits of reliable DNA data retrieval

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