DSS-induced inflammation in the colon drives a proinflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

DSS-induced inflammation in the colon drives a proinflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

Abstract Background Inflammatory bowel disease (IBD) is established to drive pathological sequelae in organ systems outside the intestine, including the central nervous system (CNS). Many patients exhibit cognitive deficits, particularly during disease flare. The connection between colonic inflammat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sarah Talley, Rasa Valiauga, Lillian Anderson, Abigail R. Cannon, Mashkoor A. Choudhry, Edward M. Campbell
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Colitis
Inflammation
Neuroinflammation
Caspase-1
S100A8/A9
Neurology. Diseases of the nervous system
RC346-429
Acceso en línea:https://doaj.org/article/1a0c1442c2bd412fa48af60fc7a37b7d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares