Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway.

Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway.

In the present study, we aim to elucidate the roles of caveolin-1(Cav-1), a 22 kDa protein in plasma membrane invaginations, in modulating neuronal differentiation of neural progenitor cells (NPCs). In the hippocampal dentate gyrus, we found that Cav-1 knockout mice revealed remarkably higher levels...

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Autores principales: Yue Li, Jianmin Luo, Wui-Man Lau, Guoqing Zheng, Shuping Fu, Ting-Ting Wang, He-Ping Zeng, Kwok-Fai So, Sookja Kim Chung, Yao Tong, Kejian Liu, Jiangang Shen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1a0c9fc3019040b3bb40a1e627eeaa00
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