Gut Microbiota–Medication Interaction in Rheumatic Diseases

Besides its contribution to the development of rheumatic diseases, the gut microbiota interact with anti-rheumatic drugs. The intestinal microbiota can directly metabolize many drugs and indirectly change drug metabolism through a complex multi-dimensional interaction with the host, thus affecting i...

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Autores principales:	Lingshu Zhang, Cong-Qiu Chu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	microbiota disease modifying anti-rheumatic drugs personalized medicine biomarkers prediction and opportunity Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/1a0d74486ac34616b400640b8bd8e5f4
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spelling	oai:doaj.org-article:1a0d74486ac34616b400640b8bd8e5f42021-12-03T06:04:38ZGut Microbiota–Medication Interaction in Rheumatic Diseases1664-322410.3389/fimmu.2021.796865https://doaj.org/article/1a0d74486ac34616b400640b8bd8e5f42021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.796865/fullhttps://doaj.org/toc/1664-3224Besides its contribution to the development of rheumatic diseases, the gut microbiota interact with anti-rheumatic drugs. The intestinal microbiota can directly metabolize many drugs and indirectly change drug metabolism through a complex multi-dimensional interaction with the host, thus affecting individual response to drug therapy and adverse effects. The focus of the current review is to address recent advances and important progress in our understanding of how the gut microbiota interact with anti-rheumatic drugs and provide perspectives on promoting precision treatment, drug discovery, and better therapy for rheumatic diseases.Lingshu ZhangLingshu ZhangCong-Qiu ChuCong-Qiu ChuFrontiers Media S.A.articlemicrobiotadisease modifying anti-rheumatic drugspersonalized medicinebiomarkersprediction and opportunityImmunologic diseases. AllergyRC581-607ENFrontiers in Immunology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	microbiota disease modifying anti-rheumatic drugs personalized medicine biomarkers prediction and opportunity Immunologic diseases. Allergy RC581-607
spellingShingle	microbiota disease modifying anti-rheumatic drugs personalized medicine biomarkers prediction and opportunity Immunologic diseases. Allergy RC581-607 Lingshu Zhang Lingshu Zhang Cong-Qiu Chu Cong-Qiu Chu Gut Microbiota–Medication Interaction in Rheumatic Diseases
description	Besides its contribution to the development of rheumatic diseases, the gut microbiota interact with anti-rheumatic drugs. The intestinal microbiota can directly metabolize many drugs and indirectly change drug metabolism through a complex multi-dimensional interaction with the host, thus affecting individual response to drug therapy and adverse effects. The focus of the current review is to address recent advances and important progress in our understanding of how the gut microbiota interact with anti-rheumatic drugs and provide perspectives on promoting precision treatment, drug discovery, and better therapy for rheumatic diseases.
format	article
author	Lingshu Zhang Lingshu Zhang Cong-Qiu Chu Cong-Qiu Chu
author_facet	Lingshu Zhang Lingshu Zhang Cong-Qiu Chu Cong-Qiu Chu
author_sort	Lingshu Zhang
title	Gut Microbiota–Medication Interaction in Rheumatic Diseases
title_short	Gut Microbiota–Medication Interaction in Rheumatic Diseases
title_full	Gut Microbiota–Medication Interaction in Rheumatic Diseases
title_fullStr	Gut Microbiota–Medication Interaction in Rheumatic Diseases
title_full_unstemmed	Gut Microbiota–Medication Interaction in Rheumatic Diseases
title_sort	gut microbiota–medication interaction in rheumatic diseases
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/1a0d74486ac34616b400640b8bd8e5f4
work_keys_str_mv	AT lingshuzhang gutmicrobiotamedicationinteractioninrheumaticdiseases AT lingshuzhang gutmicrobiotamedicationinteractioninrheumaticdiseases AT congqiuchu gutmicrobiotamedicationinteractioninrheumaticdiseases AT congqiuchu gutmicrobiotamedicationinteractioninrheumaticdiseases
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Gut Microbiota–Medication Interaction in Rheumatic Diseases

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