Inference of Bacterial Small RNA Regulatory Networks and Integration with Transcription Factor-Driven Regulatory Networks

Inference of Bacterial Small RNA Regulatory Networks and Integration with Transcription Factor-Driven Regulatory Networks

ABSTRACT Small noncoding RNAs (sRNAs) are key regulators of bacterial gene expression. Through complementary base pairing, sRNAs affect mRNA stability and translation efficiency. Here, we describe a network inference approach designed to identify sRNA-mediated regulation of transcript levels. We use...

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Autores principales: Mario L. Arrieta-Ortiz, Christoph Hafemeister, Bentley Shuster, Nitin S. Baliga, Richard Bonneau, Patrick Eichenberger
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
gene networks
global regulation
small RNAs
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/1a14f9e1bbdd44feb3ac31d3a0bb9f34
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