Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation

Nader Nassiri,1 Saeedeh Ghorbanhosseini,2 Ebrahim Jafarzadehpur,2 Sara Kavousnezhad,3 Nariman Nassiri,4 Kourosh Sheibani5 1Imam Hossein Medical Center, Shahid Beheshti University of Medical Science, Tehran, Iran; 2Department of Optometry, Iran University of Medical Sciences, Tehran, Iran; 3Vanak Ey...

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Autores principales: Nassiri N, Ghorbanhosseini S, Jafarzadehpur E, Kavousnezhad S, Sheibani K
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Publicado: Dove Medical Press 2018
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spelling oai:doaj.org-article:1a1a267235c14490b87bb959b6316fbd2021-12-02T00:12:10ZVisual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation1177-5483https://doaj.org/article/1a1a267235c14490b87bb959b6316fbd2018-03-01T00:00:00Zhttps://www.dovepress.com/visual-acuity-endothelial-cell-density-and-polymegathism-after-iris-fi-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Nader Nassiri,1 Saeedeh Ghorbanhosseini,2 Ebrahim Jafarzadehpur,2 Sara Kavousnezhad,3 Nariman Nassiri,4 Kourosh Sheibani5 1Imam Hossein Medical Center, Shahid Beheshti University of Medical Science, Tehran, Iran; 2Department of Optometry, Iran University of Medical Sciences, Tehran, Iran; 3Vanak Eye Clinic, Tehran, Iran; 4Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA, USA; 5Basir Eye Health Research Center, Basir Eye Clinic, Tehran, Iran Purpose: The purpose of this study was to evaluate the visual acuity as well as endothelial cell density (ECD) and polymegathism after iris-fixated lens (Artiflex® AC 401) implantation for correction of moderate to high myopia.Patients and methods: In this retrospective cross-sectional study, 55 eyes from 29 patients undergoing iris-fixated lens implantation for correction of myopia (−5.00 to −15.00 D) from 2007 to 2014 were evaluated. Uncorrected visual acuity, best spectacle-corrected visual acuity, refraction, ECD and polymegathism (coefficient of variation [CV] in the sizes of endothelial cells) were measured preoperatively and 6 months postoperatively.Results: In the sixth month of follow-up, the uncorrected vision acuity was 20/25 or better in 81.5% of the eyes. The best-corrected visual acuity was 20/30 or better in 96.3% of the eyes, and more than 92% of the eyes had a refraction score of ±1 D from the target refraction. The mean corneal ECD of patients before surgery was 2,803±339 cells/mm2, which changed to 2,744±369 cells/mm2 six months after surgery (p=0.142). CV in the sizes of endothelial cells before the surgery was 25.7%±7.1% and six months after surgery it was 25.9%±5.4% (p=0.857).Conclusion: Artiflex iris-fixated lens implantation is a suitable and predictable method for correction of moderate to high myopia. There was no statistically significant change in ECD and polymegathism (CV in the sizes of endothelial cells) after 6 months of follow-up. Keywords: cornea, endothelial cell, density, Artiflex, refractive surgery Nassiri NGhorbanhosseini SJafarzadehpur EKavousnezhad SNassiri NSheibani KDove Medical PressarticleCorneaendothelial celldensityArtiflexrefractive surgery.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 601-605 (2018)
institution DOAJ
collection DOAJ
language EN
topic Cornea
endothelial cell
density
Artiflex
refractive surgery.
Ophthalmology
RE1-994
spellingShingle Cornea
endothelial cell
density
Artiflex
refractive surgery.
Ophthalmology
RE1-994
Nassiri N
Ghorbanhosseini S
Jafarzadehpur E
Kavousnezhad S
Nassiri N
Sheibani K
Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation
description Nader Nassiri,1 Saeedeh Ghorbanhosseini,2 Ebrahim Jafarzadehpur,2 Sara Kavousnezhad,3 Nariman Nassiri,4 Kourosh Sheibani5 1Imam Hossein Medical Center, Shahid Beheshti University of Medical Science, Tehran, Iran; 2Department of Optometry, Iran University of Medical Sciences, Tehran, Iran; 3Vanak Eye Clinic, Tehran, Iran; 4Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA, USA; 5Basir Eye Health Research Center, Basir Eye Clinic, Tehran, Iran Purpose: The purpose of this study was to evaluate the visual acuity as well as endothelial cell density (ECD) and polymegathism after iris-fixated lens (Artiflex® AC 401) implantation for correction of moderate to high myopia.Patients and methods: In this retrospective cross-sectional study, 55 eyes from 29 patients undergoing iris-fixated lens implantation for correction of myopia (−5.00 to −15.00 D) from 2007 to 2014 were evaluated. Uncorrected visual acuity, best spectacle-corrected visual acuity, refraction, ECD and polymegathism (coefficient of variation [CV] in the sizes of endothelial cells) were measured preoperatively and 6 months postoperatively.Results: In the sixth month of follow-up, the uncorrected vision acuity was 20/25 or better in 81.5% of the eyes. The best-corrected visual acuity was 20/30 or better in 96.3% of the eyes, and more than 92% of the eyes had a refraction score of ±1 D from the target refraction. The mean corneal ECD of patients before surgery was 2,803±339 cells/mm2, which changed to 2,744±369 cells/mm2 six months after surgery (p=0.142). CV in the sizes of endothelial cells before the surgery was 25.7%±7.1% and six months after surgery it was 25.9%±5.4% (p=0.857).Conclusion: Artiflex iris-fixated lens implantation is a suitable and predictable method for correction of moderate to high myopia. There was no statistically significant change in ECD and polymegathism (CV in the sizes of endothelial cells) after 6 months of follow-up. Keywords: cornea, endothelial cell, density, Artiflex, refractive surgery 
format article
author Nassiri N
Ghorbanhosseini S
Jafarzadehpur E
Kavousnezhad S
Nassiri N
Sheibani K
author_facet Nassiri N
Ghorbanhosseini S
Jafarzadehpur E
Kavousnezhad S
Nassiri N
Sheibani K
author_sort Nassiri N
title Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation
title_short Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation
title_full Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation
title_fullStr Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation
title_full_unstemmed Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation
title_sort visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation
publisher Dove Medical Press
publishDate 2018
url https://doaj.org/article/1a1a267235c14490b87bb959b6316fbd
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AT kavousnezhads visualacuityendothelialcelldensityandpolymegathismafteririsfixatedlensimplantation
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