Molecular correlates of muscle spindle and Golgi tendon organ afferents

Coordinated movement critically depends on sensory feedback from muscle spindles (MSs) and Golgi tendon organs (GTOs) but the afferents supplying this proprioceptive feedback have remained genetically inseparable. Here the authors use single cell transcriptome analysis to reveal the molecular basis...

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Autores principales:	Katherine M. Oliver, Danny M. Florez-Paz, Tudor Constantin Badea, George Z. Mentis, Vilas Menon, Joriene C. de Nooij
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1a25f8a076bf42029aa7c592d7e11206
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spelling	oai:doaj.org-article:1a25f8a076bf42029aa7c592d7e112062021-12-02T13:34:49ZMolecular correlates of muscle spindle and Golgi tendon organ afferents10.1038/s41467-021-21880-32041-1723https://doaj.org/article/1a25f8a076bf42029aa7c592d7e112062021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21880-3https://doaj.org/toc/2041-1723Coordinated movement critically depends on sensory feedback from muscle spindles (MSs) and Golgi tendon organs (GTOs) but the afferents supplying this proprioceptive feedback have remained genetically inseparable. Here the authors use single cell transcriptome analysis to reveal the molecular basis of MS (groups Ia and II) and GTO (group Ib) afferent identities in the mouse.Katherine M. OliverDanny M. Florez-PazTudor Constantin BadeaGeorge Z. MentisVilas MenonJoriene C. de NooijNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Katherine M. Oliver Danny M. Florez-Paz Tudor Constantin Badea George Z. Mentis Vilas Menon Joriene C. de Nooij Molecular correlates of muscle spindle and Golgi tendon organ afferents
description	Coordinated movement critically depends on sensory feedback from muscle spindles (MSs) and Golgi tendon organs (GTOs) but the afferents supplying this proprioceptive feedback have remained genetically inseparable. Here the authors use single cell transcriptome analysis to reveal the molecular basis of MS (groups Ia and II) and GTO (group Ib) afferent identities in the mouse.
format	article
author	Katherine M. Oliver Danny M. Florez-Paz Tudor Constantin Badea George Z. Mentis Vilas Menon Joriene C. de Nooij
author_facet	Katherine M. Oliver Danny M. Florez-Paz Tudor Constantin Badea George Z. Mentis Vilas Menon Joriene C. de Nooij
author_sort	Katherine M. Oliver
title	Molecular correlates of muscle spindle and Golgi tendon organ afferents
title_short	Molecular correlates of muscle spindle and Golgi tendon organ afferents
title_full	Molecular correlates of muscle spindle and Golgi tendon organ afferents
title_fullStr	Molecular correlates of muscle spindle and Golgi tendon organ afferents
title_full_unstemmed	Molecular correlates of muscle spindle and Golgi tendon organ afferents
title_sort	molecular correlates of muscle spindle and golgi tendon organ afferents
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1a25f8a076bf42029aa7c592d7e11206
work_keys_str_mv	AT katherinemoliver molecularcorrelatesofmusclespindleandgolgitendonorganafferents AT dannymflorezpaz molecularcorrelatesofmusclespindleandgolgitendonorganafferents AT tudorconstantinbadea molecularcorrelatesofmusclespindleandgolgitendonorganafferents AT georgezmentis molecularcorrelatesofmusclespindleandgolgitendonorganafferents AT vilasmenon molecularcorrelatesofmusclespindleandgolgitendonorganafferents AT jorienecdenooij molecularcorrelatesofmusclespindleandgolgitendonorganafferents
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Molecular correlates of muscle spindle and Golgi tendon organ afferents

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