Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction

Protein interaction networks can identify host proteins that affect virus replication. Here, the authors compare the protein interactomes of several influenza A virus strains and identify plakophilin 2 as a restriction factor that inhibits formation of the viral polymerase complex.

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Autores principales:	Lingyan Wang, Bishi Fu, Wenjun Li, Girish Patil, Lin Liu, Martin E. Dorf, Shitao Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1a276961025844e98f7ea3311990f46d
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spelling	oai:doaj.org-article:1a276961025844e98f7ea3311990f46d2021-12-02T14:42:43ZComparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction10.1038/ncomms138762041-1723https://doaj.org/article/1a276961025844e98f7ea3311990f46d2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms13876https://doaj.org/toc/2041-1723Protein interaction networks can identify host proteins that affect virus replication. Here, the authors compare the protein interactomes of several influenza A virus strains and identify plakophilin 2 as a restriction factor that inhibits formation of the viral polymerase complex.Lingyan WangBishi FuWenjun LiGirish PatilLin LiuMartin E. DorfShitao LiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lingyan Wang Bishi Fu Wenjun Li Girish Patil Lin Liu Martin E. Dorf Shitao Li Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
description	Protein interaction networks can identify host proteins that affect virus replication. Here, the authors compare the protein interactomes of several influenza A virus strains and identify plakophilin 2 as a restriction factor that inhibits formation of the viral polymerase complex.
format	article
author	Lingyan Wang Bishi Fu Wenjun Li Girish Patil Lin Liu Martin E. Dorf Shitao Li
author_facet	Lingyan Wang Bishi Fu Wenjun Li Girish Patil Lin Liu Martin E. Dorf Shitao Li
author_sort	Lingyan Wang
title	Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
title_short	Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
title_full	Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
title_fullStr	Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
title_full_unstemmed	Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
title_sort	comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1a276961025844e98f7ea3311990f46d
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Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction

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