Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury

Body cavity macrophages reside on the serous surfaces of organs and believed to participate in organ repair following injury. Here the authors show with a fate-mapping reporter system that these cells, although accumulate at the surfaces of injured liver or lung, don’t penetrate deeply into the tiss...

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Autores principales: Hengwei Jin, Kuo Liu, Juan Tang, Xiuzhen Huang, Haixiao Wang, Qianyu Zhang, Huan Zhu, Yan Li, Wenjuan Pu, Huan Zhao, Lingjuan He, Yi Li, Shaohua Zhang, Zhenqian Zhang, Yufei Zhao, Yanqing Qin, Stefan Pflanz, Karim E. I. Kasmi, Weiyi Zhang, Zhaoyuan Liu, Florent Ginhoux, Yong Ji, Ben He, Lixin Wang, Bin Zhou
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1a384c9067664b0394d211c938d9df2a
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spelling oai:doaj.org-article:1a384c9067664b0394d211c938d9df2a2021-12-02T15:45:24ZGenetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury10.1038/s41467-021-23197-72041-1723https://doaj.org/article/1a384c9067664b0394d211c938d9df2a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23197-7https://doaj.org/toc/2041-1723Body cavity macrophages reside on the serous surfaces of organs and believed to participate in organ repair following injury. Here the authors show with a fate-mapping reporter system that these cells, although accumulate at the surfaces of injured liver or lung, don’t penetrate deeply into the tissue.Hengwei JinKuo LiuJuan TangXiuzhen HuangHaixiao WangQianyu ZhangHuan ZhuYan LiWenjuan PuHuan ZhaoLingjuan HeYi LiShaohua ZhangZhenqian ZhangYufei ZhaoYanqing QinStefan PflanzKarim E. I. KasmiWeiyi ZhangZhaoyuan LiuFlorent GinhouxYong JiBen HeLixin WangBin ZhouNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hengwei Jin
Kuo Liu
Juan Tang
Xiuzhen Huang
Haixiao Wang
Qianyu Zhang
Huan Zhu
Yan Li
Wenjuan Pu
Huan Zhao
Lingjuan He
Yi Li
Shaohua Zhang
Zhenqian Zhang
Yufei Zhao
Yanqing Qin
Stefan Pflanz
Karim E. I. Kasmi
Weiyi Zhang
Zhaoyuan Liu
Florent Ginhoux
Yong Ji
Ben He
Lixin Wang
Bin Zhou
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury
description Body cavity macrophages reside on the serous surfaces of organs and believed to participate in organ repair following injury. Here the authors show with a fate-mapping reporter system that these cells, although accumulate at the surfaces of injured liver or lung, don’t penetrate deeply into the tissue.
format article
author Hengwei Jin
Kuo Liu
Juan Tang
Xiuzhen Huang
Haixiao Wang
Qianyu Zhang
Huan Zhu
Yan Li
Wenjuan Pu
Huan Zhao
Lingjuan He
Yi Li
Shaohua Zhang
Zhenqian Zhang
Yufei Zhao
Yanqing Qin
Stefan Pflanz
Karim E. I. Kasmi
Weiyi Zhang
Zhaoyuan Liu
Florent Ginhoux
Yong Ji
Ben He
Lixin Wang
Bin Zhou
author_facet Hengwei Jin
Kuo Liu
Juan Tang
Xiuzhen Huang
Haixiao Wang
Qianyu Zhang
Huan Zhu
Yan Li
Wenjuan Pu
Huan Zhao
Lingjuan He
Yi Li
Shaohua Zhang
Zhenqian Zhang
Yufei Zhao
Yanqing Qin
Stefan Pflanz
Karim E. I. Kasmi
Weiyi Zhang
Zhaoyuan Liu
Florent Ginhoux
Yong Ji
Ben He
Lixin Wang
Bin Zhou
author_sort Hengwei Jin
title Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury
title_short Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury
title_full Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury
title_fullStr Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury
title_full_unstemmed Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury
title_sort genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1a384c9067664b0394d211c938d9df2a
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