Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy

BACKGROUND AND OBJECTIVE: Bells palsy is the most common disorder of the facial nerve, developing some acute changes in the face. Considering its probable viral etiology, antiviral therapy is recently added to the classic regimen. This study has been conducted to compare the effectiveness of two reg...

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Autores principales:	A Ahmadi Ahangar, R Saghebi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2006
Materias:	bells palsy prednisolone acyclovir Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/1a3a11eafe3d4395a92690e29c47ccff
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spelling	oai:doaj.org-article:1a3a11eafe3d4395a92690e29c47ccff2021-11-10T09:12:42ZComparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy1561-41072251-7170https://doaj.org/article/1a3a11eafe3d4395a92690e29c47ccff2006-04-01T00:00:00Zhttp://jbums.org/article-1-2554-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Bells palsy is the most common disorder of the facial nerve, developing some acute changes in the face. Considering its probable viral etiology, antiviral therapy is recently added to the classic regimen. This study has been conducted to compare the effectiveness of two regimens of prednisolone versus prednisolone plus acyclovir in the treatment of Bell’s palsy.METHODS: This clinical trial study was performed on 496 patients with Bell’s palsy who divided into two groups the first group was treated with oral prednisolone and the second group with oral prednisolone and acyclovir. The patients were evaluated at the end of the second week, first, third and sixth months after treatment. The outcome of therapy in two treated groups were compared.FINDINGS: Two hundred and forty eight patients (108 males and 140 females) with average age of 20-39 and 248 patients (135 males and 113 females) with the same mean age were treated with prednisolone and prednisolone plus acyclovir, respectively. At the end of the study, the recovery rate in the combined regimen group was 95.06% (237 patients) and in the prednisolone regimen group was 91.2% (226 patients) (p= 0.035). CONCLUSION: The result of this study shows that combination of prednisolone plus acyclovir is the preferred regimen of therapy in Bell’s palsy.A Ahmadi AhangarR SaghebiBabol University of Medical Sciencesarticlebells palsyprednisoloneacyclovirMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 8, Iss 2, Pp 36-41 (2006)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	bells palsy prednisolone acyclovir Medicine R Medicine (General) R5-920
spellingShingle	bells palsy prednisolone acyclovir Medicine R Medicine (General) R5-920 A Ahmadi Ahangar R Saghebi Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy
description	BACKGROUND AND OBJECTIVE: Bells palsy is the most common disorder of the facial nerve, developing some acute changes in the face. Considering its probable viral etiology, antiviral therapy is recently added to the classic regimen. This study has been conducted to compare the effectiveness of two regimens of prednisolone versus prednisolone plus acyclovir in the treatment of Bell’s palsy.METHODS: This clinical trial study was performed on 496 patients with Bell’s palsy who divided into two groups the first group was treated with oral prednisolone and the second group with oral prednisolone and acyclovir. The patients were evaluated at the end of the second week, first, third and sixth months after treatment. The outcome of therapy in two treated groups were compared.FINDINGS: Two hundred and forty eight patients (108 males and 140 females) with average age of 20-39 and 248 patients (135 males and 113 females) with the same mean age were treated with prednisolone and prednisolone plus acyclovir, respectively. At the end of the study, the recovery rate in the combined regimen group was 95.06% (237 patients) and in the prednisolone regimen group was 91.2% (226 patients) (p= 0.035). CONCLUSION: The result of this study shows that combination of prednisolone plus acyclovir is the preferred regimen of therapy in Bell’s palsy.
format	article
author	A Ahmadi Ahangar R Saghebi
author_facet	A Ahmadi Ahangar R Saghebi
author_sort	A Ahmadi Ahangar
title	Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy
title_short	Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy
title_full	Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy
title_fullStr	Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy
title_full_unstemmed	Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy
title_sort	comparison of the efficacy of prednisolone versus prednisolone plus acyclovir in the treatment of bells palsy
publisher	Babol University of Medical Sciences
publishDate	2006
url	https://doaj.org/article/1a3a11eafe3d4395a92690e29c47ccff
work_keys_str_mv	AT aahmadiahangar comparisonoftheefficacyofprednisoloneversusprednisoloneplusacyclovirinthetreatmentofbellspalsy AT rsaghebi comparisonoftheefficacyofprednisoloneversusprednisoloneplusacyclovirinthetreatmentofbellspalsy
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Comparison of the efficacy of Prednisolone versus Prednisolone plus Acyclovir in the treatment of Bells palsy

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