Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate

Background: Serology of streptococcal [GAS] group-A is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for streptococcal pharyngitis diagnoses. Streptococcal titers vary according to a number of factors, including age and population. In developing count...

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Autores principales:	Aziza Abdou, Mohamed Zannoun, Magdy El Ghanam
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Materias:	group-a streptococci [gas] anti-streptolysin o [aso] upper limit of normal children alexandria-governorate Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/1a3f811cbf98473da8e65bd015187926
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spelling	oai:doaj.org-article:1a3f811cbf98473da8e65bd0151879262021-12-02T10:46:43ZAssessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate2636-41742682-378010.21608/ijma.2020.42462.1163https://doaj.org/article/1a3f811cbf98473da8e65bd0151879262021-01-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_120305_1185f6001bcace89642367183b276267.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Serology of streptococcal [GAS] group-A is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for streptococcal pharyngitis diagnoses. Streptococcal titers vary according to a number of factors, including age and population. In developing countries, where GAS-induced impetigo is rare, the titers in healthy people are low in early childhood, peak in children aged 6 to 15, decrease in late adolescence and early adulthood, and then flatten off afterwards. Aim of the work: To assess Anti streptolysin-O titre in healthy school age children in Alexandria governorate. Patients and Methods: A prospective study had been performed in Alexandria Governorate and the collected sample were tested in clinical pathology Lab [Al-Azhar University Hospital, Damietta]. A total of 3000 [1540 Males, 1460 Females] serum samples had been collected from children aged 6-15 years, had been tested for Anti-streptolysin O titer [ASO] by latex. Results: ASO from 100-200 was higher with 1281 [42.7%] followed by Conclusions: We concluded that upper limit of normal [ULN] ASOT is quite high in normal Egyptian children, reaching up to 850.0 IU / ml. Mapping of upper normal levels and associated factors with increased levels could provide a clue for future planning to prevent streptococcal infection and its associated complications.Aziza AbdouMohamed ZannounMagdy El GhanamAl-Azhar University, Faculty of Medicine (Damietta)articlegroup-a streptococci [gas]anti-streptolysin o [aso]upper limit of normalchildrenalexandria-governorateMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 1, Pp 995-1000 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	group-a streptococci [gas] anti-streptolysin o [aso] upper limit of normal children alexandria-governorate Medicine (General) R5-920
spellingShingle	group-a streptococci [gas] anti-streptolysin o [aso] upper limit of normal children alexandria-governorate Medicine (General) R5-920 Aziza Abdou Mohamed Zannoun Magdy El Ghanam Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate
description	Background: Serology of streptococcal [GAS] group-A is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for streptococcal pharyngitis diagnoses. Streptococcal titers vary according to a number of factors, including age and population. In developing countries, where GAS-induced impetigo is rare, the titers in healthy people are low in early childhood, peak in children aged 6 to 15, decrease in late adolescence and early adulthood, and then flatten off afterwards. Aim of the work: To assess Anti streptolysin-O titre in healthy school age children in Alexandria governorate. Patients and Methods: A prospective study had been performed in Alexandria Governorate and the collected sample were tested in clinical pathology Lab [Al-Azhar University Hospital, Damietta]. A total of 3000 [1540 Males, 1460 Females] serum samples had been collected from children aged 6-15 years, had been tested for Anti-streptolysin O titer [ASO] by latex. Results: ASO from 100-200 was higher with 1281 [42.7%] followed by Conclusions: We concluded that upper limit of normal [ULN] ASOT is quite high in normal Egyptian children, reaching up to 850.0 IU / ml. Mapping of upper normal levels and associated factors with increased levels could provide a clue for future planning to prevent streptococcal infection and its associated complications.
format	article
author	Aziza Abdou Mohamed Zannoun Magdy El Ghanam
author_facet	Aziza Abdou Mohamed Zannoun Magdy El Ghanam
author_sort	Aziza Abdou
title	Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate
title_short	Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate
title_full	Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate
title_fullStr	Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate
title_full_unstemmed	Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate
title_sort	assessment of anti-streptolysin-o titre in healthy school-age children in alexandria governorate
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/1a3f811cbf98473da8e65bd015187926
work_keys_str_mv	AT azizaabdou assessmentofantistreptolysinotitreinhealthyschoolagechildreninalexandriagovernorate AT mohamedzannoun assessmentofantistreptolysinotitreinhealthyschoolagechildreninalexandriagovernorate AT magdyelghanam assessmentofantistreptolysinotitreinhealthyschoolagechildreninalexandriagovernorate
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Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate

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