Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF

Viruses often subvert the host immune system using molecular decoys to prevent an effective immune response. Here, the authors examine the structural details of the viral decoy receptor GIF and its antagnosim of GM-CSF and IL-2.

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Autores principales: Jan Felix, Eaazhisai Kandiah, Steven De Munck, Yehudi Bloch, Gydo C.P. van Zundert, Kris Pauwels, Ann Dansercoer, Katka Novanska, Randy J. Read, Alexandre M.J.J. Bonvin, Bjorn Vergauwen, Kenneth Verstraete, Irina Gutsche, Savvas N. Savvides
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1a41664ed7484e5ea4bc536b02b76f4a
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spelling oai:doaj.org-article:1a41664ed7484e5ea4bc536b02b76f4a2021-12-02T15:35:24ZStructural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF10.1038/ncomms132282041-1723https://doaj.org/article/1a41664ed7484e5ea4bc536b02b76f4a2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13228https://doaj.org/toc/2041-1723Viruses often subvert the host immune system using molecular decoys to prevent an effective immune response. Here, the authors examine the structural details of the viral decoy receptor GIF and its antagnosim of GM-CSF and IL-2.Jan FelixEaazhisai KandiahSteven De MunckYehudi BlochGydo C.P. van ZundertKris PauwelsAnn DansercoerKatka NovanskaRandy J. ReadAlexandre M.J.J. BonvinBjorn VergauwenKenneth VerstraeteIrina GutscheSavvas N. SavvidesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jan Felix
Eaazhisai Kandiah
Steven De Munck
Yehudi Bloch
Gydo C.P. van Zundert
Kris Pauwels
Ann Dansercoer
Katka Novanska
Randy J. Read
Alexandre M.J.J. Bonvin
Bjorn Vergauwen
Kenneth Verstraete
Irina Gutsche
Savvas N. Savvides
Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
description Viruses often subvert the host immune system using molecular decoys to prevent an effective immune response. Here, the authors examine the structural details of the viral decoy receptor GIF and its antagnosim of GM-CSF and IL-2.
format article
author Jan Felix
Eaazhisai Kandiah
Steven De Munck
Yehudi Bloch
Gydo C.P. van Zundert
Kris Pauwels
Ann Dansercoer
Katka Novanska
Randy J. Read
Alexandre M.J.J. Bonvin
Bjorn Vergauwen
Kenneth Verstraete
Irina Gutsche
Savvas N. Savvides
author_facet Jan Felix
Eaazhisai Kandiah
Steven De Munck
Yehudi Bloch
Gydo C.P. van Zundert
Kris Pauwels
Ann Dansercoer
Katka Novanska
Randy J. Read
Alexandre M.J.J. Bonvin
Bjorn Vergauwen
Kenneth Verstraete
Irina Gutsche
Savvas N. Savvides
author_sort Jan Felix
title Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
title_short Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
title_full Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
title_fullStr Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
title_full_unstemmed Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
title_sort structural basis of gm-csf and il-2 sequestration by the viral decoy receptor gif
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1a41664ed7484e5ea4bc536b02b76f4a
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