Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo

Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo

Abstract Shadoo (Sho), a member of prion protein family, has been shown to prevent embryonic lethality in Prnp 0/0 mice and to be reduced in the brains of rodents with terminal prion diseases. Sho can also affect PrP structural dynamics and can increase the prion conversion into its misfolded isofor...

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Autores principales: Anna Pepe, Rosario Avolio, Danilo Swann Matassa, Franca Esposito, Lucio Nitsch, Chiara Zurzolo, Simona Paladino, Daniela Sarnataro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1a4316d3a77d4fc7be9465ba7d6814ea
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