Optimization of online particle counting with a 3D-printed bubble trap

Particulate evaluation is needed for the approval of cardiovascular devices. Air bubbles lead to higher particle counts when light obscuration method (LOM) is used. The aim of the study was to test a custom made bubble trap that removes air bubbles (2 - 100 μm) from a flow circuit prior to online pa...

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Autores principales: Kurzhals Anja, Brandt-Wunderlich Christoph, Borowski Finja, Schmitz Klaus-Peter, Grabow Niels, Schmidt Wolfram, Gurung Jyoti
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2020
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Acceso en línea:https://doaj.org/article/1a560e52b96542749577982e1027816f
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spelling oai:doaj.org-article:1a560e52b96542749577982e1027816f2021-12-05T14:10:43ZOptimization of online particle counting with a 3D-printed bubble trap2364-550410.1515/cdbme-2020-3108https://doaj.org/article/1a560e52b96542749577982e1027816f2020-09-01T00:00:00Zhttps://doi.org/10.1515/cdbme-2020-3108https://doaj.org/toc/2364-5504Particulate evaluation is needed for the approval of cardiovascular devices. Air bubbles lead to higher particle counts when light obscuration method (LOM) is used. The aim of the study was to test a custom made bubble trap that removes air bubbles (2 - 100 μm) from a flow circuit prior to online particle counting. Artificially generated air bubbles were counted with an online particle counter with and without the bubble trap. Air bubbles were reduced by about 71 % to 91 % by using the bubble trap.Kurzhals AnjaBrandt-Wunderlich ChristophBorowski FinjaSchmitz Klaus-PeterGrabow NielsSchmidt WolframGurung JyotiDe Gruyterarticleonline particle measurementparticle countingbubble trapimplant testingMedicineRENCurrent Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 418-421 (2020)
institution DOAJ
collection DOAJ
language EN
topic online particle measurement
particle counting
bubble trap
implant testing
Medicine
R
spellingShingle online particle measurement
particle counting
bubble trap
implant testing
Medicine
R
Kurzhals Anja
Brandt-Wunderlich Christoph
Borowski Finja
Schmitz Klaus-Peter
Grabow Niels
Schmidt Wolfram
Gurung Jyoti
Optimization of online particle counting with a 3D-printed bubble trap
description Particulate evaluation is needed for the approval of cardiovascular devices. Air bubbles lead to higher particle counts when light obscuration method (LOM) is used. The aim of the study was to test a custom made bubble trap that removes air bubbles (2 - 100 μm) from a flow circuit prior to online particle counting. Artificially generated air bubbles were counted with an online particle counter with and without the bubble trap. Air bubbles were reduced by about 71 % to 91 % by using the bubble trap.
format article
author Kurzhals Anja
Brandt-Wunderlich Christoph
Borowski Finja
Schmitz Klaus-Peter
Grabow Niels
Schmidt Wolfram
Gurung Jyoti
author_facet Kurzhals Anja
Brandt-Wunderlich Christoph
Borowski Finja
Schmitz Klaus-Peter
Grabow Niels
Schmidt Wolfram
Gurung Jyoti
author_sort Kurzhals Anja
title Optimization of online particle counting with a 3D-printed bubble trap
title_short Optimization of online particle counting with a 3D-printed bubble trap
title_full Optimization of online particle counting with a 3D-printed bubble trap
title_fullStr Optimization of online particle counting with a 3D-printed bubble trap
title_full_unstemmed Optimization of online particle counting with a 3D-printed bubble trap
title_sort optimization of online particle counting with a 3d-printed bubble trap
publisher De Gruyter
publishDate 2020
url https://doaj.org/article/1a560e52b96542749577982e1027816f
work_keys_str_mv AT kurzhalsanja optimizationofonlineparticlecountingwitha3dprintedbubbletrap
AT brandtwunderlichchristoph optimizationofonlineparticlecountingwitha3dprintedbubbletrap
AT borowskifinja optimizationofonlineparticlecountingwitha3dprintedbubbletrap
AT schmitzklauspeter optimizationofonlineparticlecountingwitha3dprintedbubbletrap
AT grabowniels optimizationofonlineparticlecountingwitha3dprintedbubbletrap
AT schmidtwolfram optimizationofonlineparticlecountingwitha3dprintedbubbletrap
AT gurungjyoti optimizationofonlineparticlecountingwitha3dprintedbubbletrap
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