Structural basis for transcription initiation by bacterial ECF σ factors

Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holo...

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Autores principales: Lingting Li, Chengli Fang, Ningning Zhuang, Tiantian Wang, Yu Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1a58aa4b88894a5ead7026afa2e00b8e
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spelling oai:doaj.org-article:1a58aa4b88894a5ead7026afa2e00b8e2021-12-02T14:40:19ZStructural basis for transcription initiation by bacterial ECF σ factors10.1038/s41467-019-09096-y2041-1723https://doaj.org/article/1a58aa4b88894a5ead7026afa2e00b8e2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09096-yhttps://doaj.org/toc/2041-1723Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holoenzyme and the ECF σ factor-RNAP transcription initiation complex.Lingting LiChengli FangNingning ZhuangTiantian WangYu ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lingting Li
Chengli Fang
Ningning Zhuang
Tiantian Wang
Yu Zhang
Structural basis for transcription initiation by bacterial ECF σ factors
description Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holoenzyme and the ECF σ factor-RNAP transcription initiation complex.
format article
author Lingting Li
Chengli Fang
Ningning Zhuang
Tiantian Wang
Yu Zhang
author_facet Lingting Li
Chengli Fang
Ningning Zhuang
Tiantian Wang
Yu Zhang
author_sort Lingting Li
title Structural basis for transcription initiation by bacterial ECF σ factors
title_short Structural basis for transcription initiation by bacterial ECF σ factors
title_full Structural basis for transcription initiation by bacterial ECF σ factors
title_fullStr Structural basis for transcription initiation by bacterial ECF σ factors
title_full_unstemmed Structural basis for transcription initiation by bacterial ECF σ factors
title_sort structural basis for transcription initiation by bacterial ecf σ factors
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1a58aa4b88894a5ead7026afa2e00b8e
work_keys_str_mv AT lingtingli structuralbasisfortranscriptioninitiationbybacterialecfsfactors
AT chenglifang structuralbasisfortranscriptioninitiationbybacterialecfsfactors
AT ningningzhuang structuralbasisfortranscriptioninitiationbybacterialecfsfactors
AT tiantianwang structuralbasisfortranscriptioninitiationbybacterialecfsfactors
AT yuzhang structuralbasisfortranscriptioninitiationbybacterialecfsfactors
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