Structural basis for transcription initiation by bacterial ECF σ factors
Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holo...
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Nature Portfolio
2019
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oai:doaj.org-article:1a58aa4b88894a5ead7026afa2e00b8e2021-12-02T14:40:19ZStructural basis for transcription initiation by bacterial ECF σ factors10.1038/s41467-019-09096-y2041-1723https://doaj.org/article/1a58aa4b88894a5ead7026afa2e00b8e2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09096-yhttps://doaj.org/toc/2041-1723Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holoenzyme and the ECF σ factor-RNAP transcription initiation complex.Lingting LiChengli FangNingning ZhuangTiantian WangYu ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Lingting Li Chengli Fang Ningning Zhuang Tiantian Wang Yu Zhang Structural basis for transcription initiation by bacterial ECF σ factors |
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Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holoenzyme and the ECF σ factor-RNAP transcription initiation complex. |
format |
article |
author |
Lingting Li Chengli Fang Ningning Zhuang Tiantian Wang Yu Zhang |
author_facet |
Lingting Li Chengli Fang Ningning Zhuang Tiantian Wang Yu Zhang |
author_sort |
Lingting Li |
title |
Structural basis for transcription initiation by bacterial ECF σ factors |
title_short |
Structural basis for transcription initiation by bacterial ECF σ factors |
title_full |
Structural basis for transcription initiation by bacterial ECF σ factors |
title_fullStr |
Structural basis for transcription initiation by bacterial ECF σ factors |
title_full_unstemmed |
Structural basis for transcription initiation by bacterial ECF σ factors |
title_sort |
structural basis for transcription initiation by bacterial ecf σ factors |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/1a58aa4b88894a5ead7026afa2e00b8e |
work_keys_str_mv |
AT lingtingli structuralbasisfortranscriptioninitiationbybacterialecfsfactors AT chenglifang structuralbasisfortranscriptioninitiationbybacterialecfsfactors AT ningningzhuang structuralbasisfortranscriptioninitiationbybacterialecfsfactors AT tiantianwang structuralbasisfortranscriptioninitiationbybacterialecfsfactors AT yuzhang structuralbasisfortranscriptioninitiationbybacterialecfsfactors |
_version_ |
1718390342007390208 |