Structural basis for transcription initiation by bacterial ECF σ factors

Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holo...

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Bibliographic Details
Main Authors: Lingting Li, Chengli Fang, Ningning Zhuang, Tiantian Wang, Yu Zhang
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/1a58aa4b88894a5ead7026afa2e00b8e
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