Therapeutic delivery of siRNA with polymeric carriers to down-regulate STAT5A expression in high-risk B-cell acute lymphoblastic leukemia (B-ALL).
Overexpression and persistent activation of STAT5 play an important role in the development and progression of acute lymphoblastic leukemia (ALL), the most common pediatric cancer. Small interfering RNA (siRNA)-mediated downregulation of STAT5 represents a promising therapeutic approach for ALL to o...
Guardado en:
Autores principales: | Mahsa Mohseni, Cezary Kucharski, Remant Bahadur K C, Mohammad Nasrullah, Xiaoyan Jiang, Hasan Uludağ, Joseph Brandwein |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1a62915026d245f68c6014a1ba201dd0 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Towards Raman-Based Screening of Acute Lymphoblastic Leukemia-Type B (B-ALL) Subtypes
por: Patrycja Leszczenko, et al.
Publicado: (2021) -
Recent advances in the biology and treatment of B-cell acute lymphoblastic leukemia
por: Hefazi M, et al.
Publicado: (2018) -
B- Acute Lymphoblastic Leukemia L2 In Second Trimester of Pregnancy
por: Iraisa rosaria, et al.
Publicado: (2021) -
Transcriptional and Mutational Profiling of B-Other Acute Lymphoblastic Leukemia for Improved Diagnostics
por: Philippe Chouvarine, et al.
Publicado: (2021) -
Clinical and pharmacologic aspects of blinatumomab in the treatment of B-cell acute lymphoblastic leukemia
por: Portell CA, et al.
Publicado: (2013)