Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung

Functional diversity of tissue-resident macrophages and signals governing their ontogeny and turnover remain unknown for the majority of tissues. Here the authors describe two phenotypically and functionally distinct long-lived populations of lung interstitial macrophages and their putative blood-de...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Joey Schyns, Qiang Bai, Cecilia Ruscitti, Coraline Radermecker, Sebastiaan De Schepper, Svetoslav Chakarov, Frédéric Farnir, Dimitri Pirottin, Florent Ginhoux, Guy Boeckxstaens, Fabrice Bureau, Thomas Marichal
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/1a749755f4bd47d3a92a6cda37807131
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Functional diversity of tissue-resident macrophages and signals governing their ontogeny and turnover remain unknown for the majority of tissues. Here the authors describe two phenotypically and functionally distinct long-lived populations of lung interstitial macrophages and their putative blood-derived monocytic precursor.