Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung

Functional diversity of tissue-resident macrophages and signals governing their ontogeny and turnover remain unknown for the majority of tissues. Here the authors describe two phenotypically and functionally distinct long-lived populations of lung interstitial macrophages and their putative blood-de...

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Autores principales: Joey Schyns, Qiang Bai, Cecilia Ruscitti, Coraline Radermecker, Sebastiaan De Schepper, Svetoslav Chakarov, Frédéric Farnir, Dimitri Pirottin, Florent Ginhoux, Guy Boeckxstaens, Fabrice Bureau, Thomas Marichal
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1a749755f4bd47d3a92a6cda37807131
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spelling oai:doaj.org-article:1a749755f4bd47d3a92a6cda378071312021-12-02T15:35:51ZNon-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung10.1038/s41467-019-11843-02041-1723https://doaj.org/article/1a749755f4bd47d3a92a6cda378071312019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11843-0https://doaj.org/toc/2041-1723Functional diversity of tissue-resident macrophages and signals governing their ontogeny and turnover remain unknown for the majority of tissues. Here the authors describe two phenotypically and functionally distinct long-lived populations of lung interstitial macrophages and their putative blood-derived monocytic precursor.Joey SchynsQiang BaiCecilia RuscittiCoraline RadermeckerSebastiaan De SchepperSvetoslav ChakarovFrédéric FarnirDimitri PirottinFlorent GinhouxGuy BoeckxstaensFabrice BureauThomas MarichalNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joey Schyns
Qiang Bai
Cecilia Ruscitti
Coraline Radermecker
Sebastiaan De Schepper
Svetoslav Chakarov
Frédéric Farnir
Dimitri Pirottin
Florent Ginhoux
Guy Boeckxstaens
Fabrice Bureau
Thomas Marichal
Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
description Functional diversity of tissue-resident macrophages and signals governing their ontogeny and turnover remain unknown for the majority of tissues. Here the authors describe two phenotypically and functionally distinct long-lived populations of lung interstitial macrophages and their putative blood-derived monocytic precursor.
format article
author Joey Schyns
Qiang Bai
Cecilia Ruscitti
Coraline Radermecker
Sebastiaan De Schepper
Svetoslav Chakarov
Frédéric Farnir
Dimitri Pirottin
Florent Ginhoux
Guy Boeckxstaens
Fabrice Bureau
Thomas Marichal
author_facet Joey Schyns
Qiang Bai
Cecilia Ruscitti
Coraline Radermecker
Sebastiaan De Schepper
Svetoslav Chakarov
Frédéric Farnir
Dimitri Pirottin
Florent Ginhoux
Guy Boeckxstaens
Fabrice Bureau
Thomas Marichal
author_sort Joey Schyns
title Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
title_short Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
title_full Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
title_fullStr Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
title_full_unstemmed Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
title_sort non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1a749755f4bd47d3a92a6cda37807131
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