The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis

Yen-Tze Liu,1 Pei-Yu Yang,2 Yu-Wen Yang,1 Hung-Yu Sun,1 I-Ching Lin1,3,4 1Department of Family Medicine, Changhua Christian Hospital, 2Department of Laboratory, Show Chwan Memorial Hospital, Changhua City, 3School of Medicine, Chung Shan Medical University, Taichung City, 4School of Medicine, Kaohs...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Liu YT, Yang PY, Yang YW, Sun HY, Lin IC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Nephrolithiasis Metabolic Syndrome X Cross-sectional study primary health care Preventive Health Services Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/1a76f30caed64ebdb7b96986fb0f264b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1a76f30caed64ebdb7b96986fb0f264b
record_format	dspace
spelling	oai:doaj.org-article:1a76f30caed64ebdb7b96986fb0f264b2021-12-02T11:44:55ZThe association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis1178-203Xhttps://doaj.org/article/1a76f30caed64ebdb7b96986fb0f264b2017-01-01T00:00:00Zhttps://www.dovepress.com/the-association-of-nephrolithiasis-with-metabolic-syndrome-and-its-com-peer-reviewed-article-TCRMhttps://doaj.org/toc/1178-203XYen-Tze Liu,1 Pei-Yu Yang,2 Yu-Wen Yang,1 Hung-Yu Sun,1 I-Ching Lin1,3,4 1Department of Family Medicine, Changhua Christian Hospital, 2Department of Laboratory, Show Chwan Memorial Hospital, Changhua City, 3School of Medicine, Chung Shan Medical University, Taichung City, 4School of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan Background: Metabolic syndrome is a worldwide disorder and also the major risk factor of several systemic diseases. Evidence identifying the association between metabolic syndrome and nephrolithiasis is lacking, especially in Taiwan.Aim: The aim of this study was to investigate the association between nephrolithiasis and metabolic syndrome and its components.Design and setting: This was a cross-sectional study conducted in the Health Examination Department of a medical center in Changhua, Taiwan, from January 2010 to December 2010.Methods: We reviewed the medical records of patients who had visited the Health Examination Center of Changhua Christian Hospital in 2010. A total of 3,886 individuals were enrolled. According to the exclusion criteria, those with an age <20 years and an abnormal renal function were excluded. A total of 3,793 subjects were included. All P-values are two tailed, and P<0.05 was defined as statistically significant.Results: The results showed a correlation between nephrolithiasis and metabolic syndrome and its components. The multivariate-adjusted odds ratio (OR) (95% confidence interval [CI]) of metabolic syndrome for nephrolithiasis was 1.318 (1.083–1.604), with a P-value of 0.006. Larger waist circumference (multivariable-adjusted OR 1.338; 95% CI 1.098–1.631; P=0.004), higher blood pressure (multivariable-adjusted OR 1.333; 95% CI 1.106–1.607; P=0.003), and increased fasting glucose (multivariable-adjusted OR 1.276; 95% CI 1.054–1.546; P=0.01) were associated with nephrolithiasis.Conclusion: This is the first study in Taiwan to investigate the relationship between metabolic syndrome and nephrolithiasis. The mechanism is controversial, and several hypotheses are offered. Adequate lifestyle modification and proper treatment in metabolic syndrome management may both contribute to nephrolithiasis prevention. Keywords: nephrolithiasis, metabolic syndrome, cross-sectional study, primary health care, preventive health servicesLiu YTYang PYYang YWSun HYLin ICDove Medical PressarticleNephrolithiasisMetabolic Syndrome XCross-sectional studyprimary health carePreventive Health ServicesTherapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 13, Pp 41-48 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nephrolithiasis Metabolic Syndrome X Cross-sectional study primary health care Preventive Health Services Therapeutics. Pharmacology RM1-950
spellingShingle	Nephrolithiasis Metabolic Syndrome X Cross-sectional study primary health care Preventive Health Services Therapeutics. Pharmacology RM1-950 Liu YT Yang PY Yang YW Sun HY Lin IC The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis
description	Yen-Tze Liu,1 Pei-Yu Yang,2 Yu-Wen Yang,1 Hung-Yu Sun,1 I-Ching Lin1,3,4 1Department of Family Medicine, Changhua Christian Hospital, 2Department of Laboratory, Show Chwan Memorial Hospital, Changhua City, 3School of Medicine, Chung Shan Medical University, Taichung City, 4School of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan Background: Metabolic syndrome is a worldwide disorder and also the major risk factor of several systemic diseases. Evidence identifying the association between metabolic syndrome and nephrolithiasis is lacking, especially in Taiwan.Aim: The aim of this study was to investigate the association between nephrolithiasis and metabolic syndrome and its components.Design and setting: This was a cross-sectional study conducted in the Health Examination Department of a medical center in Changhua, Taiwan, from January 2010 to December 2010.Methods: We reviewed the medical records of patients who had visited the Health Examination Center of Changhua Christian Hospital in 2010. A total of 3,886 individuals were enrolled. According to the exclusion criteria, those with an age <20 years and an abnormal renal function were excluded. A total of 3,793 subjects were included. All P-values are two tailed, and P<0.05 was defined as statistically significant.Results: The results showed a correlation between nephrolithiasis and metabolic syndrome and its components. The multivariate-adjusted odds ratio (OR) (95% confidence interval [CI]) of metabolic syndrome for nephrolithiasis was 1.318 (1.083–1.604), with a P-value of 0.006. Larger waist circumference (multivariable-adjusted OR 1.338; 95% CI 1.098–1.631; P=0.004), higher blood pressure (multivariable-adjusted OR 1.333; 95% CI 1.106–1.607; P=0.003), and increased fasting glucose (multivariable-adjusted OR 1.276; 95% CI 1.054–1.546; P=0.01) were associated with nephrolithiasis.Conclusion: This is the first study in Taiwan to investigate the relationship between metabolic syndrome and nephrolithiasis. The mechanism is controversial, and several hypotheses are offered. Adequate lifestyle modification and proper treatment in metabolic syndrome management may both contribute to nephrolithiasis prevention. Keywords: nephrolithiasis, metabolic syndrome, cross-sectional study, primary health care, preventive health services
format	article
author	Liu YT Yang PY Yang YW Sun HY Lin IC
author_facet	Liu YT Yang PY Yang YW Sun HY Lin IC
author_sort	Liu YT
title	The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis
title_short	The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis
title_full	The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis
title_fullStr	The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis
title_full_unstemmed	The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis
title_sort	association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/1a76f30caed64ebdb7b96986fb0f264b
work_keys_str_mv	AT liuyt theassociationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT yangpy theassociationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT yangyw theassociationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT sunhy theassociationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT linic theassociationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT liuyt associationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT yangpy associationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT yangyw associationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT sunhy associationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis AT linic associationofnephrolithiasiswithmetabolicsyndromeanditscomponentsacrosssectionalanalysis
_version_	1718395267971022848

The association of nephrolithiasis with metabolic syndrome and its components: a cross-sectional analysis

Ejemplares similares