The circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders
Antenatal glucocorticoid therapy is indicated for mothers at risk of preterm delivery. Here, the authors show that the circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders later in life in mice and in a retrospective observational study in human infants.
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Nature Portfolio
2020
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oai:doaj.org-article:1a77159f7cad4c18bbc372837a3c2bf12021-12-02T15:33:05ZThe circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders10.1038/s41467-020-17429-52041-1723https://doaj.org/article/1a77159f7cad4c18bbc372837a3c2bf12020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17429-5https://doaj.org/toc/2041-1723Antenatal glucocorticoid therapy is indicated for mothers at risk of preterm delivery. Here, the authors show that the circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders later in life in mice and in a retrospective observational study in human infants.Mariana AstizIsabel HeydeMats Ingmar FortmannVerena BossungClaudia RollAnja SteinBerthold GrüttnerWolfgang GöpelChristoph HärtelJonas ObleserHenrik OsterNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
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Science Q Mariana Astiz Isabel Heyde Mats Ingmar Fortmann Verena Bossung Claudia Roll Anja Stein Berthold Grüttner Wolfgang Göpel Christoph Härtel Jonas Obleser Henrik Oster The circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders |
description |
Antenatal glucocorticoid therapy is indicated for mothers at risk of preterm delivery. Here, the authors show that the circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders later in life in mice and in a retrospective observational study in human infants. |
format |
article |
author |
Mariana Astiz Isabel Heyde Mats Ingmar Fortmann Verena Bossung Claudia Roll Anja Stein Berthold Grüttner Wolfgang Göpel Christoph Härtel Jonas Obleser Henrik Oster |
author_facet |
Mariana Astiz Isabel Heyde Mats Ingmar Fortmann Verena Bossung Claudia Roll Anja Stein Berthold Grüttner Wolfgang Göpel Christoph Härtel Jonas Obleser Henrik Oster |
author_sort |
Mariana Astiz |
title |
The circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders |
title_short |
The circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders |
title_full |
The circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders |
title_fullStr |
The circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders |
title_full_unstemmed |
The circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders |
title_sort |
circadian phase of antenatal glucocorticoid treatment affects the risk of behavioral disorders |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/1a77159f7cad4c18bbc372837a3c2bf1 |
work_keys_str_mv |
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