High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries

Average Nucleotide Identity (ANI) is a robust and useful measure to gauge genetic relatedness between two genomes. Here, the authors develop FastANI, a method to compute ANI using alignment-free approximate sequence mapping, and show 95% ANI is an accurate threshold for demarcating prokaryotic speci...

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Autores principales:	Chirag Jain, Luis M. Rodriguez-R, Adam M. Phillippy, Konstantinos T. Konstantinidis, Srinivas Aluru
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1a91648286dc4ad7b362fb1f3a14aece
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spelling	oai:doaj.org-article:1a91648286dc4ad7b362fb1f3a14aece2021-12-02T17:33:03ZHigh throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries10.1038/s41467-018-07641-92041-1723https://doaj.org/article/1a91648286dc4ad7b362fb1f3a14aece2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07641-9https://doaj.org/toc/2041-1723Average Nucleotide Identity (ANI) is a robust and useful measure to gauge genetic relatedness between two genomes. Here, the authors develop FastANI, a method to compute ANI using alignment-free approximate sequence mapping, and show 95% ANI is an accurate threshold for demarcating prokaryotic species by analyzing about 90,000 prokaryotic genomes.Chirag JainLuis M. Rodriguez-RAdam M. PhillippyKonstantinos T. KonstantinidisSrinivas AluruNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chirag Jain Luis M. Rodriguez-R Adam M. Phillippy Konstantinos T. Konstantinidis Srinivas Aluru High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
description	Average Nucleotide Identity (ANI) is a robust and useful measure to gauge genetic relatedness between two genomes. Here, the authors develop FastANI, a method to compute ANI using alignment-free approximate sequence mapping, and show 95% ANI is an accurate threshold for demarcating prokaryotic species by analyzing about 90,000 prokaryotic genomes.
format	article
author	Chirag Jain Luis M. Rodriguez-R Adam M. Phillippy Konstantinos T. Konstantinidis Srinivas Aluru
author_facet	Chirag Jain Luis M. Rodriguez-R Adam M. Phillippy Konstantinos T. Konstantinidis Srinivas Aluru
author_sort	Chirag Jain
title	High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
title_short	High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
title_full	High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
title_fullStr	High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
title_full_unstemmed	High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
title_sort	high throughput ani analysis of 90k prokaryotic genomes reveals clear species boundaries
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1a91648286dc4ad7b362fb1f3a14aece
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_version_	1718380048083320832

High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries

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