The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Vacuoles

The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Vacuoles

ABSTRACT Chlamydia trachomatis delivers multiple type 3 secreted effector proteins to host epithelial cells to manipulate cytoskeletal functions, membrane dynamics, and signaling pathways. TepP is the most abundant effector protein secreted early in infection, but its molecular function is poorly un...

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Autores principales: Victoria Carpenter, Yi-Shan Chen, Lee Dolat, Raphael H. Valdivia
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
CrkL
PI3K
PIP3
Src kinases
T3S effector
type I IFN
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/1a9812cd31a041fbade3db49bbc9394d
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