Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair

The yeast Rad1–Rad10 complex has multiple roles in DNA damage repair. Here the authors uncover mutants that uncouple the roles in UV excision repair and non-NER functions.

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Autores principales: Ja-Hwan Seol, Cory Holland, Xiaolei Li, Christopher Kim, Fuyang Li, Melisa Medina-Rivera, Robin Eichmiller, Ignacio F. Gallardo, Ilya J. Finkelstein, Paul Hasty, Eun Yong Shim, Jennifer A. Surtees, Sang Eun Lee
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Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1aa8a55b041d446c9bd15181548a0127
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spelling oai:doaj.org-article:1aa8a55b041d446c9bd15181548a01272021-12-02T14:39:43ZDistinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair10.1038/s41467-018-04327-02041-1723https://doaj.org/article/1aa8a55b041d446c9bd15181548a01272018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04327-0https://doaj.org/toc/2041-1723The yeast Rad1–Rad10 complex has multiple roles in DNA damage repair. Here the authors uncover mutants that uncouple the roles in UV excision repair and non-NER functions.Ja-Hwan SeolCory HollandXiaolei LiChristopher KimFuyang LiMelisa Medina-RiveraRobin EichmillerIgnacio F. GallardoIlya J. FinkelsteinPaul HastyEun Yong ShimJennifer A. SurteesSang Eun LeeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ja-Hwan Seol
Cory Holland
Xiaolei Li
Christopher Kim
Fuyang Li
Melisa Medina-Rivera
Robin Eichmiller
Ignacio F. Gallardo
Ilya J. Finkelstein
Paul Hasty
Eun Yong Shim
Jennifer A. Surtees
Sang Eun Lee
Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair
description The yeast Rad1–Rad10 complex has multiple roles in DNA damage repair. Here the authors uncover mutants that uncouple the roles in UV excision repair and non-NER functions.
format article
author Ja-Hwan Seol
Cory Holland
Xiaolei Li
Christopher Kim
Fuyang Li
Melisa Medina-Rivera
Robin Eichmiller
Ignacio F. Gallardo
Ilya J. Finkelstein
Paul Hasty
Eun Yong Shim
Jennifer A. Surtees
Sang Eun Lee
author_facet Ja-Hwan Seol
Cory Holland
Xiaolei Li
Christopher Kim
Fuyang Li
Melisa Medina-Rivera
Robin Eichmiller
Ignacio F. Gallardo
Ilya J. Finkelstein
Paul Hasty
Eun Yong Shim
Jennifer A. Surtees
Sang Eun Lee
author_sort Ja-Hwan Seol
title Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair
title_short Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair
title_full Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair
title_fullStr Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair
title_full_unstemmed Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair
title_sort distinct roles of xpf-ercc1 and rad1-rad10-saw1 in replication-coupled and uncoupled inter-strand crosslink repair
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/1aa8a55b041d446c9bd15181548a0127
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