Structures in G proteins important for subtype selective receptor binding and subsequent activation

With chimeric approach and biophysical (FRET) techniques, Jelinek, Mösslein & Bünemann elucidate coupling selectivity determinants of G proteins for two Gq-coupled receptors. They conclude that various regions, especially outside of the C-terminal tail of the Gα subunit, collectively affect G-pr...

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Autores principales: Volker Jelinek, Nadja Mösslein, Moritz Bünemann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1ab50e3107bc4d848ea8d927ed419368
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