Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion.

Actinomyosin activity is an important driver of cell locomotion and has been shown to promote collective cell migration of epithelial sheets as well as single cell migration and tumor cell invasion. However, the molecular mechanisms underlying activation of cortical myosin to stimulate single cell m...

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Autores principales: Stephen J Terry, Ahmed Elbediwy, Ceniz Zihni, Andrew R Harris, Maryse Bailly, Guillaume T Charras, Maria S Balda, Karl Matter
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/1ab7cf95323a412fa97309259fa7759c
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