The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

Age is one of the strongest risk factors for severe illness from COVID-19. By integrating human lung transcriptomes with experimental data on SARS-CoV-2, the authors pinpoint specific age-associated factors that could contribute to the heightened severity of COVID-19 in older populations.

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Detalles Bibliográficos
Autores principales:	Ryan D. Chow, Medha Majety, Sidi Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1ac48135f6d342e19f2405cc2d35983e
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spelling	oai:doaj.org-article:1ac48135f6d342e19f2405cc2d35983e2021-12-02T11:56:18ZThe aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-210.1038/s41467-020-20323-92041-1723https://doaj.org/article/1ac48135f6d342e19f2405cc2d35983e2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20323-9https://doaj.org/toc/2041-1723Age is one of the strongest risk factors for severe illness from COVID-19. By integrating human lung transcriptomes with experimental data on SARS-CoV-2, the authors pinpoint specific age-associated factors that could contribute to the heightened severity of COVID-19 in older populations.Ryan D. ChowMedha MajetySidi ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ryan D. Chow Medha Majety Sidi Chen The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2
description	Age is one of the strongest risk factors for severe illness from COVID-19. By integrating human lung transcriptomes with experimental data on SARS-CoV-2, the authors pinpoint specific age-associated factors that could contribute to the heightened severity of COVID-19 in older populations.
format	article
author	Ryan D. Chow Medha Majety Sidi Chen
author_facet	Ryan D. Chow Medha Majety Sidi Chen
author_sort	Ryan D. Chow
title	The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2
title_short	The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2
title_full	The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2
title_fullStr	The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2
title_full_unstemmed	The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2
title_sort	aging transcriptome and cellular landscape of the human lung in relation to sars-cov-2
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1ac48135f6d342e19f2405cc2d35983e
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The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

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