Modeling the Dynamic Digestive System Microbiome

“Modeling the Dynamic Digestive System Microbiome” is a hands-on activity designed to demonstrate the dynamics of microbiome ecology using dried pasta and beans to model disturbance events in the human digestive system microbiome. This exercise demonstrates how microbiome diversity is influenced by:...

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Autor principal:	Anne M. Estes
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2015
Materias:	Special aspects of education LC8-6691 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/1ad5c85e1911484fb9fc48237c733f19
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spelling	oai:doaj.org-article:1ad5c85e1911484fb9fc48237c733f192021-11-15T15:04:03ZModeling the Dynamic Digestive System Microbiome10.1128/jmbe.v16i2.9081935-78851935-7877https://doaj.org/article/1ad5c85e1911484fb9fc48237c733f192015-12-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/jmbe.v16i2.908https://doaj.org/toc/1935-7877https://doaj.org/toc/1935-7885“Modeling the Dynamic Digestive System Microbiome” is a hands-on activity designed to demonstrate the dynamics of microbiome ecology using dried pasta and beans to model disturbance events in the human digestive system microbiome. This exercise demonstrates how microbiome diversity is influenced by: 1) niche availability and habitat space and 2) a major disturbance event, such as antibiotic use. Students use a pictorial key to examine prepared models of digestive system microbiomes to determine what the person with the microbiome “ate.” Students then model the effect of taking antibiotics by removing certain “antibiotic sensitive” pasta. Finally, they add in “environmental microbes” or “native microbes” to recolonize the digestive system, determine how resilient their model microbome community is to disturbance, and discuss the implications. Throughout the exercise, students discuss differences in the habitat space available and microbiome community diversity. This exercise can be modified to discuss changes in the microbiome due to diet shifts and the emergence of antibiotic resistance in more depth.Anne M. EstesAmerican Society for MicrobiologyarticleSpecial aspects of educationLC8-6691Biology (General)QH301-705.5ENJournal of Microbiology & Biology Education, Vol 16, Iss 2, Pp 271-273 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Special aspects of education LC8-6691 Biology (General) QH301-705.5
spellingShingle	Special aspects of education LC8-6691 Biology (General) QH301-705.5 Anne M. Estes Modeling the Dynamic Digestive System Microbiome
description	“Modeling the Dynamic Digestive System Microbiome” is a hands-on activity designed to demonstrate the dynamics of microbiome ecology using dried pasta and beans to model disturbance events in the human digestive system microbiome. This exercise demonstrates how microbiome diversity is influenced by: 1) niche availability and habitat space and 2) a major disturbance event, such as antibiotic use. Students use a pictorial key to examine prepared models of digestive system microbiomes to determine what the person with the microbiome “ate.” Students then model the effect of taking antibiotics by removing certain “antibiotic sensitive” pasta. Finally, they add in “environmental microbes” or “native microbes” to recolonize the digestive system, determine how resilient their model microbome community is to disturbance, and discuss the implications. Throughout the exercise, students discuss differences in the habitat space available and microbiome community diversity. This exercise can be modified to discuss changes in the microbiome due to diet shifts and the emergence of antibiotic resistance in more depth.
format	article
author	Anne M. Estes
author_facet	Anne M. Estes
author_sort	Anne M. Estes
title	Modeling the Dynamic Digestive System Microbiome
title_short	Modeling the Dynamic Digestive System Microbiome
title_full	Modeling the Dynamic Digestive System Microbiome
title_fullStr	Modeling the Dynamic Digestive System Microbiome
title_full_unstemmed	Modeling the Dynamic Digestive System Microbiome
title_sort	modeling the dynamic digestive system microbiome
publisher	American Society for Microbiology
publishDate	2015
url	https://doaj.org/article/1ad5c85e1911484fb9fc48237c733f19
work_keys_str_mv	AT annemestes modelingthedynamicdigestivesystemmicrobiome
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Modeling the Dynamic Digestive System Microbiome

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