Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe
Current sensors for intracellular H2O2 are not sensitive enough to detect all biologically relevant H2O2 fluctuations. Here the authors develop a peroxiredoxin-2-based FRET probe that is sensitive enough to measure changes in H2O2 concentration in response to the cancer therapeutic piperlongumine.
Guardado en:
Autores principales: | Troy F. Langford, Beijing K. Huang, Joseph B. Lim, Sun Jin Moon, Hadley D. Sikes |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1ada60e3af9c4daab6f468fb7f0175c1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The sulfiredoxin-peroxiredoxin redox system regulates the stemness and survival of colon cancer stem cells
por: In-Sung Song, et al.
Publicado: (2021) -
A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex
por: Deepti Talwar, et al.
Publicado: (2020) -
The role of peroxiredoxin II in chemoresistance of breast cancer cells
por: Wang T, et al.
Publicado: (2014) -
Light-sensing via hydrogen peroxide and a peroxiredoxin
por: Kristofer Bodvard, et al.
Publicado: (2017) -
Insights Into the Detection Selectivity of Redox and Non-redox Based Probes for the Superoxide Anion Using Coumarin and Chromone as the Fluorophores
por: Yuchen Wang, et al.
Publicado: (2021)