Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women

Aim. To study the association between vascular endothelial growth factor (VEGF) and cytokine (IL1B, IL4, IL6, IL10 and TNFA)gene polymorphism combinations with type 2 diabetes mellitus (T2DM) in women. Materials and methods. 374 Caucasian women without carbohydrate metabolism disorders from 23 to...

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Autores principales:	Vladimir Iosifovich Konenkov, Alla Vladimirovna Shevchenko, Victor Fedorovich Prokof'ev, Vadim Valer'evich Klimontov, Maksim Alexandrovich Korolev, Olga Nikolaevna Fazullina, Svetlana Alexandrovna Lapsina, Elena Anatol'evna Koroleva
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2012
Materias:	type 2 diabetes mellitus gene polymorphism growth factors cytokines Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/1ae1aad294bc47faa8e277502664a9a4
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spelling	oai:doaj.org-article:1ae1aad294bc47faa8e277502664a9a42021-11-14T09:00:17ZAssociations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women2072-03512072-037810.14341/2072-0351-6079https://doaj.org/article/1ae1aad294bc47faa8e277502664a9a42012-09-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6079https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To study the association between vascular endothelial growth factor (VEGF) and cytokine (IL1B, IL4, IL6, IL10 and TNFA)gene polymorphism combinations with type 2 diabetes mellitus (T2DM) in women. Materials and methods. 374 Caucasian women without carbohydrate metabolism disorders from 23 to 68 years of age and 212 womenwith T2DM from 28 to 69 years of age were included in the study. The combinations of polymorphism А-2578С, С+936Т in VEGFgene with polymorphism in IL1B С-31Т, IL4 С-590Т, IL6 G-174C, IL10 A-592C and А-1082G, TNFA А-238G, A-308G and A-863Cwere studied. Results. Analysis revealed 52 combined genetic variations with different rate of occurrence between diabetic and control groups(рVladimir Iosifovich KonenkovAlla Vladimirovna ShevchenkoVictor Fedorovich Prokof'evVadim Valer'evich KlimontovMaksim Alexandrovich KorolevOlga Nikolaevna FazullinaSvetlana Alexandrovna LapsinaElena Anatol'evna KorolevaEndocrinology Research Centrearticletype 2 diabetes mellitusgene polymorphismgrowth factorscytokinesNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 15, Iss 3, Pp 4-10 (2012)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 2 diabetes mellitus gene polymorphism growth factors cytokines Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 2 diabetes mellitus gene polymorphism growth factors cytokines Nutritional diseases. Deficiency diseases RC620-627 Vladimir Iosifovich Konenkov Alla Vladimirovna Shevchenko Victor Fedorovich Prokof'ev Vadim Valer'evich Klimontov Maksim Alexandrovich Korolev Olga Nikolaevna Fazullina Svetlana Alexandrovna Lapsina Elena Anatol'evna Koroleva Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women
description	Aim. To study the association between vascular endothelial growth factor (VEGF) and cytokine (IL1B, IL4, IL6, IL10 and TNFA)gene polymorphism combinations with type 2 diabetes mellitus (T2DM) in women. Materials and methods. 374 Caucasian women without carbohydrate metabolism disorders from 23 to 68 years of age and 212 womenwith T2DM from 28 to 69 years of age were included in the study. The combinations of polymorphism А-2578С, С+936Т in VEGFgene with polymorphism in IL1B С-31Т, IL4 С-590Т, IL6 G-174C, IL10 A-592C and А-1082G, TNFA А-238G, A-308G and A-863Cwere studied. Results. Analysis revealed 52 combined genetic variations with different rate of occurrence between diabetic and control groups(р
format	article
author	Vladimir Iosifovich Konenkov Alla Vladimirovna Shevchenko Victor Fedorovich Prokof'ev Vadim Valer'evich Klimontov Maksim Alexandrovich Korolev Olga Nikolaevna Fazullina Svetlana Alexandrovna Lapsina Elena Anatol'evna Koroleva
author_facet	Vladimir Iosifovich Konenkov Alla Vladimirovna Shevchenko Victor Fedorovich Prokof'ev Vadim Valer'evich Klimontov Maksim Alexandrovich Korolev Olga Nikolaevna Fazullina Svetlana Alexandrovna Lapsina Elena Anatol'evna Koroleva
author_sort	Vladimir Iosifovich Konenkov
title	Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women
title_short	Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women
title_full	Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women
title_fullStr	Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women
title_full_unstemmed	Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women
title_sort	associations of vascular endothelial growth factor (vegf) gene and cytokine (il-1b, il-4, il-6, il-10, tnfa) genes combinations with type 2 diabetes mellitus in women
publisher	Endocrinology Research Centre
publishDate	2012
url	https://doaj.org/article/1ae1aad294bc47faa8e277502664a9a4
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Associations of vascular endothelial growth factor (VEGF) gene and cytokine (IL-1B, IL-4, IL-6, IL-10, TNFA) genes combinations with type 2 diabetes mellitus in women

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