Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks

The molecular mechanisms regulating mesenchymal cell movements are unclear. Here, the authors show in chicken feather elongation that SHH/WNT signalling establishes gap-junctions, enabling synchronized Ca2 + oscillations to emerge for and in turn coordinating directed cell migration.

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Autores principales:	Ang Li, Jung-Hwa Cho, Brian Reid, Chun-Chih Tseng, Lian He, Peng Tan, Chao-Yuan Yeh, Ping Wu, Yuwei Li, Randall B. Widelitz, Yubin Zhou, Min Zhao, Robert H. Chow, Cheng-Ming Chuong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1ae526f8bfa046a1a703cf53a9ece664
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spelling	oai:doaj.org-article:1ae526f8bfa046a1a703cf53a9ece6642021-12-02T15:33:45ZCalcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks10.1038/s41467-018-07661-52041-1723https://doaj.org/article/1ae526f8bfa046a1a703cf53a9ece6642018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07661-5https://doaj.org/toc/2041-1723The molecular mechanisms regulating mesenchymal cell movements are unclear. Here, the authors show in chicken feather elongation that SHH/WNT signalling establishes gap-junctions, enabling synchronized Ca2 + oscillations to emerge for and in turn coordinating directed cell migration.Ang LiJung-Hwa ChoBrian ReidChun-Chih TsengLian HePeng TanChao-Yuan YehPing WuYuwei LiRandall B. WidelitzYubin ZhouMin ZhaoRobert H. ChowCheng-Ming ChuongNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ang Li Jung-Hwa Cho Brian Reid Chun-Chih Tseng Lian He Peng Tan Chao-Yuan Yeh Ping Wu Yuwei Li Randall B. Widelitz Yubin Zhou Min Zhao Robert H. Chow Cheng-Ming Chuong Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks
description	The molecular mechanisms regulating mesenchymal cell movements are unclear. Here, the authors show in chicken feather elongation that SHH/WNT signalling establishes gap-junctions, enabling synchronized Ca2 + oscillations to emerge for and in turn coordinating directed cell migration.
format	article
author	Ang Li Jung-Hwa Cho Brian Reid Chun-Chih Tseng Lian He Peng Tan Chao-Yuan Yeh Ping Wu Yuwei Li Randall B. Widelitz Yubin Zhou Min Zhao Robert H. Chow Cheng-Ming Chuong
author_facet	Ang Li Jung-Hwa Cho Brian Reid Chun-Chih Tseng Lian He Peng Tan Chao-Yuan Yeh Ping Wu Yuwei Li Randall B. Widelitz Yubin Zhou Min Zhao Robert H. Chow Cheng-Ming Chuong
author_sort	Ang Li
title	Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks
title_short	Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks
title_full	Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks
title_fullStr	Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks
title_full_unstemmed	Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks
title_sort	calcium oscillations coordinate feather mesenchymal cell movement by shh dependent modulation of gap junction networks
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1ae526f8bfa046a1a703cf53a9ece664
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Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks

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