The role of systematic reviews in pharmacovigilance planning and Clinical Trials Authorisation application: example from the SLEEPS trial.

<h4>Background</h4>Adequate sedation is crucial to the management of children requiring assisted ventilation on Paediatric Intensive Care Units (PICU). The evidence-base of randomised controlled trials (RCTs) in this area is small and a trial was planned to compare midazolam and clonidin...

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Autores principales: Carrol Gamble, Andrew Wolf, Ian Sinha, Catherine Spowart, Paula Williamson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/1aedb1291627467d9f3180aa74fe1891
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