Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus

Medicinal plants play a fundamental part in health sectors via the management of different infectious diseases because of their wide plenitude wellspring of bioactive phytochemicals. Research activities on them have got attention throughout the world in the present days in search of low-cost and saf...

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Autor principal: Bikash Adhikari
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/1af1b92ab8f040adb5a8c84608d5a64b
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spelling oai:doaj.org-article:1af1b92ab8f040adb5a8c84608d5a64b2021-11-08T02:37:01ZRoles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus2090-907110.1155/2021/2691525https://doaj.org/article/1af1b92ab8f040adb5a8c84608d5a64b2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2691525https://doaj.org/toc/2090-9071Medicinal plants play a fundamental part in health sectors via the management of different infectious diseases because of their wide plenitude wellspring of bioactive phytochemicals. Research activities on them have got attention throughout the world in the present days in search of low-cost and safe compounds for the management of diabetes. This is the literature-based analysis of alkaloids from medicinal plants in preventive or treatment approaches to diabetes. The most abundant and diversified group of secondary metabolites, i.e., alkaloids, show antidiabetic activity through the inhibition of enzymes (α-amylase, α-glucosidase, aldose reductase, dipeptidyl peptidase-IV, and protein tyrosine phosphatase-1B); inhibition of advanced glycation end products; increment of insulin secretion and its sensitivity; enhancement of glucose uptake; and their antioxidant ability. The study is useful for the examination of dynamic alkaloids for the advancement of a new medication for mankind.Bikash AdhikariHindawi LimitedarticleChemistryQD1-999ENJournal of Chemistry, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Chemistry
QD1-999
spellingShingle Chemistry
QD1-999
Bikash Adhikari
Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus
description Medicinal plants play a fundamental part in health sectors via the management of different infectious diseases because of their wide plenitude wellspring of bioactive phytochemicals. Research activities on them have got attention throughout the world in the present days in search of low-cost and safe compounds for the management of diabetes. This is the literature-based analysis of alkaloids from medicinal plants in preventive or treatment approaches to diabetes. The most abundant and diversified group of secondary metabolites, i.e., alkaloids, show antidiabetic activity through the inhibition of enzymes (α-amylase, α-glucosidase, aldose reductase, dipeptidyl peptidase-IV, and protein tyrosine phosphatase-1B); inhibition of advanced glycation end products; increment of insulin secretion and its sensitivity; enhancement of glucose uptake; and their antioxidant ability. The study is useful for the examination of dynamic alkaloids for the advancement of a new medication for mankind.
format article
author Bikash Adhikari
author_facet Bikash Adhikari
author_sort Bikash Adhikari
title Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus
title_short Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus
title_full Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus
title_fullStr Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus
title_full_unstemmed Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus
title_sort roles of alkaloids from medicinal plants in the management of diabetes mellitus
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/1af1b92ab8f040adb5a8c84608d5a64b
work_keys_str_mv AT bikashadhikari rolesofalkaloidsfrommedicinalplantsinthemanagementofdiabetesmellitus
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