A spike-timing-dependent plasticity rule for dendritic spines

The structural organization of excitatory inputs supporting spike-timing-dependent plasticity (STDP) in dendritic spines remains unknown. Using a spine STDP protocol, the authors uncover the STDP rules for single, clustered and distributed dendritic spines in the basal dendrites of layer 5 pyramidal...

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Autores principales: Sabrina Tazerart, Diana E. Mitchell, Soledad Miranda-Rottmann, Roberto Araya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1af94f76cce8499a8694fd8b04ec24ec
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Sumario:The structural organization of excitatory inputs supporting spike-timing-dependent plasticity (STDP) in dendritic spines remains unknown. Using a spine STDP protocol, the authors uncover the STDP rules for single, clustered and distributed dendritic spines in the basal dendrites of layer 5 pyramidal neurons in juvenile mice.