Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation
Metazoan genomes contain many clusters of conserved noncoding elements. Here, the authors provide evidence that these clusters coincide with distinct topologically associating domains in humans and Drosophila, revealing a conserved regulatory genomic architecture.
Guardado en:
Autores principales: | Nathan Harmston, Elizabeth Ing-Simmons, Ge Tan, Malcolm Perry, Matthias Merkenschlager, Boris Lenhard |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1b04c3b1a6a64b378ed9795e790183ff |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Spitzenkörper assembly mechanisms reveal conserved features of fungal and metazoan polarity scaffolds
por: Peng Zheng, et al.
Publicado: (2020) -
Topological control of extreme waves
por: Giulia Marcucci, et al.
Publicado: (2019) -
Metazoan parasites of freshwater ornamental fishes
por: Florindo,Maitê Coelho, et al.
Publicado: (2017) -
Determinants of promoter and enhancer transcription directionality in metazoans
por: Mahmoud M. Ibrahim, et al.
Publicado: (2018) -
Evolution of metazoan oxygen-sensing involved a conserved divergence of VHL affinity for HIF1α and HIF2α
por: Daniel Tarade, et al.
Publicado: (2019)